TY -的T1 -睡眠呼吸障碍和肺动脉高压JF -欧洲呼吸杂志》乔和J - 10.1183/13993003.02258 -2020欧元六世- 57 - 1 SP - 2002258 AU -柴Adir AU -马克·亨伯特盟Ari Chaouat Y1 - 2021/01/01 UR - //www.qdcxjkg.com/content/57/1/2002258.abstract N2 -睡眠呼吸紊乱(作为)包括阻塞性呼吸暂停,呼吸暂停和睡眠不足。这些夜间事件有可能增加肺动脉压(PAP)在睡眠中也在清醒状态。“纯”阻塞性睡眠呼吸暂停综合征(群)负责一个小增加PAP的临床影响尚未被证实。相比之下,在肥胖低通气综合征(OHS)或重叠综合症协会(慢性阻塞性肺疾病(COPD)和阻塞性睡眠呼吸暂停(OSA)),夜间呼吸事件导致肺动脉高压(PH)的发展,这通常是严重的。在后一种情况下,作为治疗是必要的为了提高肺血液动力学。肺动脉高血压患者慢性血栓栓塞肺动脉高压(PAH)或(CTEPH)作为发展的风险。阻塞性和中央呼吸暂停以及恶化ventilation-perfusion不匹配,可以观察到在睡眠中。应该有一个强烈的怀疑作为这样的患者人群;然而,睡眠研究精确的迹象和记录保持指定的类型。群的诊断患者的多环芳烃或CTEPH应该鼓励持续正压通气(CPAP)治疗。 The presence of isolated nocturnal hypoxaemia should also prompt the initiation of long-term oxygen therapy. These treatments are likely to avoid worsening of PH; however, it is prudent not to treat central apnoea and Cheyne–Stokes respiration (CSR) with adaptive servo-ventilation in patients with chronic right-heart failure because of a potential risk of serious adverse effects from such treatment.In this review we will consider the current knowledge of the consequences of SBDs on pulmonary haemodynamics in patients with and without chronic respiratory disease (group 3 of the clinical classification of PH) and the effect of treatments of respiratory events during sleep on PH. The prevalence and consequences of SBDs in PAH and CTEPH (groups 1 and 4 of the clinical classification of PH, respectively), as well as therapeutic options, will also be discussed.In some clinical situations, important to identify, sleep-related breathing disorders can be responsible for severe pulmonary haemodynamic consequences. In these situations, it is important to treat apnoeas, hypopnoeas and nocturnal oxygen desaturations. https://bit.ly/30akkoM ER -