TY - JOUR T1 -航空旅行相关结核病事件随访-有效性和结果:系统综述JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.00013-2020 SP - 2000013 AU - Maynard-Smith, Laura AU - Brown, Colin Stewart AU - Harris, Ross Jeremy AU - Hodkinson, Peter AU - Tamne, Surinder AU - Anderson, Sarah R. AU - Zenner，Dominik Y1 - 20/01/01 UR - //www.qdcxjkg.com/content/early/2020/11/19/13993003.00013-2020.abstract N2 -背景世界卫生组织(世卫组织)建议对在航空旅行中可能接触传染性结核病(TB)病例的乘客进行随访。众所周知，这既耗时又困难，而且随着每年往返结核病高流行国家的航班和乘客数量的增加，这种情况越来越严重。目的本文系统地回顾了飞机暴露活动性肺结核后接触者追踪调查的文献。通过回顾没有潜在结核危险因素的接触者的阳性结果，评估了飞行中传播的证据。数据来源&对Medline、EMBASE、BIOSIS、Cochrane Library和Database of Systematic Reviews进行检索，研究设计、指标病例特征、飞行时间或发表日期均不受限制。结果共纳入文献22篇，索引病例469例，接触者15 889人。所有接触者中只有26.4%的人在接触后完成了筛查。在所有已确定的接触者中，单次结核菌素皮肤试验(TST)阳性或飞行传播所致TST转化的率在0.19% (95%CI 0.13-0.27)至0.74% (95%CI 0.61-0.88)之间(随机效应荟萃分析中为0.00%，95%CI 0.00-0.00和0.13%，95%CI 0.00-0.61)。主要的限制是报告的异质性。主要发现的结论和影响启动调查的标准背后的证据薄弱，而且已广泛证明积极筛选接触者是劳动密集型的，不太可能有效。根据我们的发现，在飞机接触后，正式的全面接触追踪可能作用有限。这篇手稿最近已被《欧洲呼吸杂志》接受发表。 It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.Conflict of interest: Dr. Maynard-Smith has nothing to disclose.Conflict of interest: Dr. Brown has nothing to disclose.Conflict of interest: Dr. Harris has nothing to disclose.Conflict of interest: Dr. Hodkinson has nothing to disclose.Conflict of interest: Dr. Tamne has nothing to disclose.Conflict of interest: Dr. Zenner has nothing to disclose.Conflict of interest: Dr. Anderson has nothing to disclose. ER -