RT Journal第SR电子T1改变治疗多药抗性结核JF欧洲呼吸杂志Jo Eur Respir J FD欧洲呼吸学会SP 2001394 Do 10.1183/13993003.01394-2020 VO 56是5 A1 Kwak,Nichwon A1 Winters,Nicholas188bet官网地址A1 Campbell,Jonathon R. A1 Chan,Edward D. A1 Gegia,Medea A1 Lege,Christoph A1 Lee,Myungsun A1 Milanov,Vladimir A1 Menzies,Dick A1 Yim,Jae-Joon YR 2020 UL //www.qdcxjkg.com/ Content/56/5/2001394.Abstract AB的目的是分析国民背景下的多药(MDR)/利福平抗性(RR)抗性(RR)抗性(TB)治疗和结果的时间变化经济地位。我们分析了合作组在37个国家的MDR / RR-TB患者MDR-TB治疗中进行了荟萃分析的荟萃分析的数据。该数据由三个国家收入水平(低/中高中,高中)分类,并按照治疗启动时间(2001-2003,2004-2006,2007-2009,2010-2012和2013-2015进行分组)。分析了研究期的时间趋势。使用随机效应的广义线性混合模型计算不同收入群体的治疗成功的可能性。总,9036名患者分析。在研究期间,世界卫生组织推荐的群药物(左氧氟沙星/莫西沙星,BEDAQUILINE和LINZOLID)在所有收入群体中提高和治疗结果的增加。2001 - 2003年至2013 - 2015年期间,治疗成功率从低/低收入国家的60%增加到78%,从中高收入国家的40%到67%,73%到81%在高收入国家。在早些时候,中高收入国家的治疗成功概率低于低/低收入国家的概率,但2010年后没有观察到差异。然而,高收入国家持续更高的概率 treatment success compared to upper-middle income countries.Improved treatment outcomes and greater uptake of group A drugs were observed over time for patients with MDR/RR-TB at all income levels. However, treatment outcomes are still unsatisfactory, especially in upper-middle-income countries.Introduction of group A drugs is probably responsible for improved outcomes, even in resource-poor countries. However, a gap in treatment outcomes, which could not be fully explained by group A drugs, persists between high- and upper-middle-income countries https://bit.ly/2XJpO8U