@article {Kwak2001394, author = {Kwak, Nakwon and Winters, Nicholas and Campbell, Jonathon R. and Chan, Edward D. and Gegia, Medea and Lange, Christoph and Lee, Myungsun and Milanov, Vladimir and Menzies, Dick and Yim,jae-joon},title = {根据国民收入},抗多药的抗性结核病的变化,卷= {56},number = {5},Elocation-id = {2001394},年= {2020},doi = {2020},doi ={10.1183/13993003.01394-2020},Publisher = {欧188bet官网地址洲呼吸社会},摘要= {这项研究的目的是分析对多药耐药(MDR)/Rifampin-抗性(RR) - 抗性(RR) - Tuberculiss-tuberculiss-tuberculiss-tubculculiss-t和compiss的时间变化。(TB)在国家经济状况的背景下。我们分析了由合作小组收集的数据,用于对来自37个国家/地区的MDR/RR-TB患者进行MDR-TB治疗中的个别患者数据的荟萃分析。数据按三个国民收入水平(低/下中间,上层和高)进行了分层,并按治疗时间开始(2001 {\ textendash} 2003,2004 {\ textendash} 2006,2006,2007 {\ textendash}2009,2010 {\ textendash} 2012和2013 {\ textendash} 2015)。分析了研究期间的时间趋势。随着时间的推移,使用具有随机效应的广义线性混合模型计算了不同收入组的治疗成功率。在分析中,总共包括9036名患者。在研究期间,世界卫生组织推荐的A组药物(左氧氟沙星/莫西法沙星,Bedaquiline和lineZolid)的使用增加了,所有收入组的治疗结果都得到了改善。在2001年{\ textendash} 2003年至2013年{\ textendash} 2015年,低 - /下部中部收入国家/地区的治疗成功率从60 \%\%\%上升到78%\%,上层中间的40 \%\%\%- 收入国家,高收入国家的73 \%至81 \%。在早期,中高中收入国家的治疗成功可能性低于低/下中等收入国家,但在2010年之后没有差异。但是,高收入国家的可能性持续更高的可能性 treatment success compared to upper-middle income countries.Improved treatment outcomes and greater uptake of group A drugs were observed over time for patients with MDR/RR-TB at all income levels. However, treatment outcomes are still unsatisfactory, especially in upper-middle-income countries.Introduction of group A drugs is probably responsible for improved outcomes, even in resource-poor countries. However, a gap in treatment outcomes, which could not be fully explained by group A drugs, persists between high- and upper-middle-income countries https://bit.ly/2XJpO8U}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/56/5/2001394}, eprint = {//www.qdcxjkg.com/content/56/5/2001394.full.pdf}, journal = {European Respiratory Journal} }