体内TY -的T1 - < em > < / em > p的示范ulmonary microvascular involvement in COVID-19 using dual-energy computed tomography JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.02608-2020 VL - 56 IS - 4 SP - 2002608 AU - Si-Mohamed, Salim AU - Chebib, Nader AU - Sigovan, Monica AU - Zumbihl, Lea AU - Turquier, Ségoléne AU - Boccalini, Sara AU - Boussel, Loic AU - Mornex, Jean-Francois AU - Cottin, Vincent AU - Douek, Philippe Y1 - 2020/10/01 UR - //www.qdcxjkg.com/content/56/4/2002608.abstract N2 - Vascular involvement in coronavirus disease 2019 (COVID-19) has been suggested by several observations, such as the high rate of pulmonary embolism [1], the prothrombotic state and the proinflammatory biological profile [2, 3], as well as the pathological findings of severe endothelial injury and diffuse thrombosis [4]. Dual-energy computed tomography (DECT) allows specific imaging of the iodinated contrast agent distribution within the lung, which has been demonstrated as a surrogate marker of lung perfusion [5, 6]. Therefore, our goal was to assess in vivo pulmonary microvascular involvement in patients with COVID-19 pneumonia by using DECT and to determine whether vascular changes vary during the course of the disease.In COVID-19 pneumonia, dual-energy computed tomography has shown two patterns of lung perfusion along the course of the disease: an increase in perfusion blood volume (PBV) with ground-glass opacities and a decrease in PBV with consolidation https://bit.ly/2Zh0XcIWe thank Valerie Leitman (University of Lyon) for contributions to manuscript editing, and Adeline Mansuy (Hospices civils de Lyon) for the research proposal submission. ER -