PT - JOURNAL ARTICLE AU - Yogeswaran, Athiththan AU - Tello, Khodr AU - Sommer, Natascha AU - Ghofrani, Hossein Ardeschir AU - Seeger, Werner AU - Richter, Manuel Jonas AU - Gall，亨宁TI -深入危险分层的肺动脉高血压援助- 10.1183/13993003.国会- 2020.3974 DP - 2020 9月07 TA -欧洲呼吸杂志PG - 3974 VI - 56 IP - 5 64 4099 //www.qdcxjkg.com/content/56/suppl_64/3974.short 4100 - //www.qdcxjkg.com/content/56/suppl_64/3974.full所以和欧元J2020 9月07;56 AB导论:肺动脉高压指南推荐基于风险分层的治疗决策。建议的风险分层方案已在几个现实生活PAH队列中得到验证，证实了其在基线和随访期间的风险适应性决策方面的有效性。然而，目前尚不清楚中危患者是应作为高危患者治疗还是作为低危患者治疗。因此，我们旨在调查6分钟步行距离(SMWd)和TAPSE是否可以将中度危险患者分为低-中-和高-中组。方法:我们回顾性分析进入Giessen PH登记的PAH事件患者。考虑血流动力学参数、超声心动图参数、WHO功能等级、SMWd和BNP进行风险分层。使用R (The R Foundation, Vienna, Austria)和SPSS (Version 26, IBM, Armonk, USA)进行了适当的统计分析。结果:302例PAH患者(58±15岁，65%为女性)纳入分析。低危(96例)、中危(180例)和高危(18例)患者的5年生存率分别为69%、58%和22%。 Interestingly, stratifying intermediate-risk patients using SMWd and TAPSE allowed to distinguish between low-intermediate and high-intermediate patients (5-year survival 67% and 27%).Conclusion: 5-year survival did not differ significantly between low- and low-intermediate as well as high- and high-intermediate risk patients. Hence, risk stratification into four groups (low, low-intermediate, high-intermediate and high risk) using SMWd and TAPSE for focused stratification of intermediate risk patients is a straight-forward and simple tool for in-depth risk stratification in PAH.FootnotesCite this article as: European Respiratory Journal 2020; 56: Suppl. 64, 3974.This abstract was presented at the 2020 ERS International Congress, in session “Respiratory viruses in the "pre COVID-19" era”.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).