TY -的T1 -孤独的肺结节成像方法和光学fibre-based技术摩根富林明的角色——欧洲呼吸杂志》乔和J - 10.1183/13993003.02537 -2020欧元SP - 2002537 AU -费尔南德斯,苏珊AU -威廉姆斯,Gareth AU -威廉姆斯,埃尔韦拉盟-埃利希,Katjana盟——石头,詹姆斯盟——Finlayson尼尔非盟-布拉德利,马克AU -汤姆森,罗伯特·r . AU - Akram Ahsan r . AU -达利瓦,凯文Y1 - 2020/01/01 UR - //www.qdcxjkg.com/content/early/2020/10/02/13993003.02537 - 2020. -抽象N2 -孤独的肺结节(SPN)的临床挑战,没有单一的临床体征或辐射特性,明确标识的良性恶性SPN。肺癌的早期发现有巨大影响生存的结果。因此,及时诊断,有极大的兴趣和治疗恶性spn。目前诊断途径包括支气管/经胸廓的组织切片或辐射监测,可与次优诊断产量、医疗费用和患者的焦虑。尖端技术需要破坏,改善现有的护理途径。光学fibre-based技术,可以通过支气管镜或胸廓的针的工作通道,可能在spn患者提供先进的诊断能力。光学endomicroscopy autofluorescence-based成像技术,展示了在spn体内肺泡结构异常。等替代光学指纹识别方法、时间分辨荧光光谱和fluorescence-lifetime成像显微镜显示肺癌的承诺从周围的健康组织。同时fibre-based喇曼光谱学使实时描述spn的体内。Fibre-based技术有可能使原位描述和实时显微成像的spn,这可以帮助立即spn患者的治疗决策。 This review discusses advances in current imaging modalities for evaluating SPNs, including computed tomography (CT) and positron emission tomography-CT. It explores the emergence of optical fibre-based technologies, and discusses their potential role in patients with SPNs and suspected lung cancer.FootnotesThis manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.Conflict of interest: Dr. Fernandes reports grants from MRC, grants from Boston Scientific, during the conduct of the study.Conflict of interest: Dr. Williams reports In addition, Dr. Williams has a patent Planned pending.Conflict of interest: Dr. Williams reports In addition, Dr. Williams has a patent Planned pending.Conflict of interest: Dr. Ehrlich has nothing to disclose.Conflict of interest: Dr. Stone reports grants from EPSRC, grants from Boston Scientific, during the conduct of the study; In addition, Dr. Stone has a patent Imaging Fibre issued.Conflict of interest: Dr. Finlayson reports grants from EPSRC, during the conduct of the study; other from Prothea-X, outside the submitted work.Conflict of interest: Dr. Bradley reports grants from MRC, grants from Boston Scientific, grants from EPSRC, during the conduct of the study.Conflict of interest: Dr. Thomson reports grants from University of Edinburgh (I have an honorary position), during the conduct of the study.Conflict of interest: Dr. Akram reports grants from academic grants, during the conduct of the study.Conflict of interest: Dr. Dhaliwal reports grants from MRC, grants from Boston Scientific, grants from EPSRC, other from Mauna Kea Technologies, during the conduct of the study. ER -