@article {德Muynck2001720,作者= {德Muynck,Benedicte和Van Herck,安克和Sacreas,Annelore和海格尔,托拜厄斯和克斯,詹恩和Vanstapel,阿诺和Verleden,斯泰恩E.和Neyrinck阿恩P.和Ceulemans,劳伦斯J.和Van Raemdonck,德克E.和Lagrou,Katrien和Vanaudenaerde,巴特M.和Verleden,吉尔特M.和Vos的,罗宾},编辑= {,},标题= {成功根除假单胞菌铜绿改善肺移植后的结果:回顾性队列分析},体积= {56},数= {4},elocation-ID = {2001720},年= {2020},DOI = {10.1183 / 13993003.01720-2020},出版商= {欧洲呼吸协会},188bet官网地址抽象= {肺移植(LTX)后长期存活是由慢性肺同种异体移植功能障碍(CLAD)发展而受阻。绿脓杆菌是CLAD的危险因素。因此,我们研究P.消灭绿脓杆菌对复合自由和移植survival.Patients谁接受1991年7月,和2月至2016年第一LTX的效果,并且是无包层根据铜绿假单胞菌存在进行回顾性分类2011年9月,至九月间呼吸道样本,2016年铜绿假单胞菌阳性的患者按以下针对性的抗生素治疗消灭体育铜绿假单胞菌的成功随后分层。CLAD和无移植物存活率被铜绿假单胞菌阳性和铜绿假单胞菌阴性患者之间进行比较;和患者有无P.根除成功绿脓杆菌之间。此外,肺功能在第一年期间(N = 443)中的溶液再与铜绿假单胞菌阳性患者(n = 95相比,铜绿假单胞菌阴性患者的两个自由groups.CLAD生存以下铜绿假单胞菌评估隔离)(p = 0.045)。 Graft survival of P. aeruginosa-negative patients (n=443, 82\%) was better compared with P. aeruginosa-positive patients (n=95, 18\%) (p\<0.0001). Similarly, P. aeruginosa-eradicated patients demonstrated longer CLAD-free and graft survival compared with patients with persistent P. aeruginosa. Pulmonary function was higher in successfully P. aeruginosa-eradicated patients compared with unsuccessfully eradicated patients (p=0.035).P. aeruginosa eradication after LTx improves CLAD-free and graft survival and maintains pulmonary function. Therefore, early P. aeruginosa detection and eradication should be pursued.Presence of P. aeruginosa in respiratory samples after lung transplantation is associated with worse outcomes. Successful eradication improves outcomes and pulmonary function. Therefore, early treatment of P. aeruginosa should be pursued. https://bit.ly/2XuDPG2}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/56/4/2001720}, eprint = {//www.qdcxjkg.com/content/56/4/2001720.full.pdf}, journal = {European Respiratory Journal} }