TY - JOUR T1 - Normal spirometry predictive values for the Western Indian adult population JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.02129-2019 VL - 56 IS - 3 SP - 1902129 AU - Agarwal, Dhiraj AU - Parker,Richard A. Au -Pinnock,Hilary au -Roy,Sudipto au -Ghorpade,Deesha au -Salvi,Sundeep au -Khatavkar,Parag au -Juvekar -Juvekar,Sanjay A2-,Y1-,Y1- 2020/09/09/01 UR -HTTP:// HTTP:// HTTP:// HTTP://.ersjournals.com/content/56/3/1902129.Abstract N2-肺活量测定法的解释涉及比较肺功能参数与预测值以确定疾病的存在/严重性。全球肺功能倡议(GLI)为3至95岁的健康个体提供了参考方程,但以多个人群的形式强调了印度是一个“特定群体”,需要进一步的数据。我们的目的是在印度西部农村成年人口中得出肺活量测定法的预测方程。我们使用了先前收集的肺活量测定法(2008- 2012年),从瓦杜健康和人口统计学监测系统中从1258名健康成年人(18岁及以上)中获得。我们使用通用的位置,尺度和形状(GAMLSS)方法构建了1 s(FEV1),强制生命力(FVC)和FEV1/FVC的强迫呼气量的性别分层预测方程与GLI种族代码1(白色高加索人)和5(其他/混合)相比,每个结果都作为年龄和身高的函数。是可比的。年龄和身高都可以预测平均FEV1和FVC;对于女性,反应的变异也取决于年龄。 FEV1/FVC appears to have a very strong age effect, highlighting the limitations of using a fixed 0.7 cut-off value.The use of GLI normal values may result in overdiagnosis of lung disease in this population. We recommend that the values and equations generated from this study should be used by physicians in their routine practice for diagnosing disease and its severity in adults from the Western Indian population.The Western Indian adult population appears to have lower lung volumes compared to the Euro-American population. Use of GLI normal values may result in overdiagnosis of respiratory disease and locally derived equations should be used in clinical practice. https://bit.ly/3aMAN4s ER -