% 0期刊文章%本卢%一个李Ting-Dong % Shu-Fa郑%苏盈盈%一个刘魏Zhi-Yong李% %一个范Yu % Sheng-Xiang Ge % Qian-Da邹%人民币全%一个沙林% Cong-Ming香港% Xiang-Yang姚明% Xue-Jie张%丁慧吴%郭良齐周%一个婷婷李Wang-Heng侯% % Ya-Li张% Shi-Yin张%一个剑风扇% 6张% Ning-Shao夏%陈昱% T血清学特点SARS-CoV-2感染暴露和post-symptom后出现2020% % D R 10.1183/13993003.00763 J欧洲呼吸杂志-2020% % P 2000763 V % 56% 2% N X背景及时诊断严重急性呼吸系统综合症冠状病毒2 (SARS-CoV-2)感染是治疗和预防的先决条件。抗体的血清学特征和补充诊断价值测试RNA测试需要证明。方法连续PCR-confirmed冠状病毒疾病患者血清80 2019 (COVID-19)收集在浙江大学第一附属医院,杭州,中国。总抗体(Ab)、IgM和免疫球蛋白抗体SARS-CoV-2被检测到,在感染和抗体动力学描述。结果为Ab血清转化速率,IgM和免疫球蛋白98.8%,分别为93.8%和93.8%。第一个可发觉的血清学标记是Ab,其次是IgM和免疫球蛋白,平均血清转化时间为15日,18 - 20天邮报曝光(d.p.e)或9,10和12天开始(d.p.o),分别。的抗体水平d.p.o 6点开始迅速增加。伴随着病毒载量下降。患者在疾病的早期阶段(鹿d.p.o), Ab显示最高的敏感性(64.1%)相比IgM和免疫球蛋白(为33.3%;p < 0.001)。Ab的敏感性,IgM和免疫球蛋白增加到100%,96.7%和93.3%,分别2周后。 When the same antibody type was detected, no significant difference was observed between enzyme-linked immunosorbent assays and other forms of immunoassays.Conclusions A typical acute antibody response is induced during SARS-CoV-2 infection. Serology testing provides an important complement to RNA testing in the later stages of illness for pathogenic-specific diagnosis and helpful information to evaluate the adapted immunity status of patients.Antibody responses were induced after SARS-CoV-2 infection, and the complementary diagnostic value of the antibody test to the RNA test was observed. Antibody tests are critical to the clinical management and control of SARS-CoV-2 infection and COVID-19. https://bit.ly/3fQZwZp %U //www.qdcxjkg.com/content/erj/56/2/2000763.full.pdf