%0杂志文章%A松本，武石%A村濑，木彦%A田原，安春%A南，拓间%A金井，修生%A竹山，高桥广文%A滨田，谷泽聪%A若村，友子%A小美，直子%A濑，和也%A川口，高久%A tsusumi，高信%A森田，高桥聪%A中山，平井雄，丰裕%A松田，文彦%A Chin，睡眠呼吸障碍和代谢共病在东亚的性别和绝经状态:长滨研究D 2020 R 10.1183/13993003.02251-2019 J欧洲呼吸杂志P 1902251 %V 56% N 2 %X众所周知，睡眠呼吸障碍(SDB)的患病率在肥胖或代谢共病患者中增加。然而，根据肥胖的严重程度，SDB患病率与合并症相关的增加方式尚不清楚。这项横断面研究评估了7713名社区参与者使用夜间血氧测量≥2晚。通过腕式活动记录仪(actio - odi3%)测定经睡眠时间校正后的3%氧饱和度指数来评估SDB。SDB严重程度以actio - odi3%定义。肥胖定义为体重指数≥25 kg·m−2。正常、轻、中、重度SDB患病率分别为41.0% (95% CI 39.9 ~ 42.1%)、46.9%(45.8 ~ 48.0%)、10.1%(9.5 ~ 10.8%)、2.0%(1.7 ~ 2.3%)，性别差异显著(男性>绝经后女性>绝经前女性)。高血压、糖尿病和代谢综合征等共病与中重度SDB的患病率独立相关，其中任何一种疾病与肥胖的巧合都与中重度SDB的较高概率相关(高血压OR 8.2, 95% CI 6.6-10.2;糖尿病OR 7.8, 95% CI 5.6-10.9;代谢综合征OR 6.7, 95% CI 5.2-8.6)。 Dyslipidaemia in addition to obesity was not additively associated with the prevalence of moderate-to-severe SDB. The number of antihypertensive drugs was associated with SDB (p for trend <0.001). Proportion of a high cumulative percentage of sleep time with oxygen saturation measured by pulse oximetry <90% increased, even among moderate-to-severe SDB with increases in obesity.Metabolic comorbidities contribute to SDB regardless of the degree of obesity. We should recognise the extremely high prevalence of moderate-to-severe SDB in patients with obesity and metabolic comorbidities.Metabolic comorbidities (hypertension, diabetes, dyslipidaemia, metabolic syndrome) contribute to SDB regardless of obesity grade. We should recognise the extremely high prevalence of moderate–severe SDB in patients with obesity and metabolic comorbidities. https://bit.ly/3586fJg %U //www.qdcxjkg.com/content/erj/56/2/1902251.full.pdf