TY -的T1 -没有胰岛素抵抗的迹象in idiopathic pulmonary arterial hypertension with preserved physical activity JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.01228-2019 VL - 55 IS - 6 SP - 1901228 AU - Nagy, Bence M. AU - Kovacs, Gabor AU - Tornyos, Adrienn AU - Svehlikova, Eva AU - Foris, Vasile AU - Nagaraj, Chandran AU - Kwapiszewska, Grazyna AU - Pieber, Thomas R. AU - Olschewski, Andrea AU - Olschewski, Horst Y1 - 2020/06/01 UR - //www.qdcxjkg.com/content/55/6/1901228.abstract N2 - There is growing interest in metabolic profiling in pulmonary arterial hypertension (PAH) due to current findings suggesting significant metabolic changes causing pulmonary arterial remodelling and linking PAH to insulin resistance [1]. Such findings may have major impact on future diagnostic and therapeutic strategies for PAH. However, most studies have enrolled patients with severe disease whose reduced physical activity may have a profound effect on insulin sensitivity.Insulin resistance might not be a primary cause of severe remodelling of the small pulmonary arteries in idiopathic PAH http://bit.ly/3c8elot ER -