慢性阻塞性肺疾病吸入皮质类固醇戒断:欧洲188bet官网地址呼吸学会指南摩根富林明欧洲呼吸杂志乔和J FD欧元欧洲呼吸学会SP 2000351 10.1183/13993003.00351 -2020签证官55是6 A1查尔默斯,詹姆斯d·A1香鼠,Irena f . A1 Franssen熔化卷A1詹森Wim A1 Pavord,伊恩•A1 Rigau大卫A1麦克唐奈,梅丽莎·J·A1罗氏,尼古拉斯A1罪,不d . A1 Stolz Daiana A1 Suissa,萨米A1 Wedzicha,门当户对的A1 Miravitlles,摘要AB吸入性皮质激素(ICS)联合支气管扩张剂可降低慢性阻塞性肺疾病(COPD)加重的频率。然而，有证据表明，ic经常用于疗效尚未确定的患者。因此，有必要对COPD患者使用ICS进行个体化治疗，并考虑在没有明确指示的患者中停用ICS。本报告报告了欧洲呼吸学会对COPD患者停用I188bet官网地址CS的建议。我们进行了全面的证据综合来总结与以下问题相关的所有可用证据:COPD患者是否应该停用ICS ?使用等级(建议、评估、发展和评价的等级)方法对证据进行评估，结果在证据档案中进行总结。证据综合被讨论，并由一个在COPD和指南方法学方面有专门知识的委员会制定建议。在考虑了可取和不可取后果、证据质量以及干预措施的可行性和可接受性之后，指南小组作出: 1) conditional recommendation for the withdrawal of ICS in patients with COPD without a history of frequent exacerbations, 2) strong recommendation not to withdraw ICS in patients with blood eosinophil counts ≥300 eosinophils·µL−1 and 3) strong recommendation to treat with one or two long-acting bronchodilators if ICS are withdrawn.A conditional recommendation indicates that there was uncertainty about the balance of desirable and undesirable consequences of the intervention, and that well-informed patients may make different choices regarding whether to have or not have the specific intervention.This ERS short guideline summarises the evidence and provides recommendations for ICS withdrawal in patients with COPD https://bit.ly/33R3M5w