采用的％0期刊论文％A Brazzale，丹尼J.％A Seccombe，利M.％A威尔士，利安％A LANTERI，西莉亚J.％A法拉，克劳德S.％A Ruehland，沃伦R.％T影响全球肺功能倡议一氧化碳转移因子％d 2020％R 10.1183 / 13993003.01905-2019％Ĵ欧洲呼吸杂志％P 1901905％V 55％N 5％X最近公布的全球肺功能倡议（GLI的解释2017参考方程）一氧化碳转移因子（TLCO）参考方程提供采用一个电流，所有年龄，广泛适用参考集的机会。The aim of this study was to document the effect of changing to GLI from commonly utilised reference equations on the interpretation of TLCO results.33 863 TLCO results (48% female, 88% Caucasian, n=930 aged <18 years) from clinical pulmonary function laboratories within three Australian teaching hospitals were analysed. The lower limit of normal (LLN) and proportion of patients with a TLCO below this value were calculated using GLI and other commonly used reference equations.The average TLCO LLN for GLI was similar or lower than the other equations, with the largest difference seen for Crapo equations (median: −1.25, IQR: −1.64, −0.86 mmol·min−1·kPa−1). These differences resulted in altered rates of reduced TLCO for GLI particularly for adults (+1.9% versus Miller to −27.6% versus Crapo), more so than for children (−0.8% versus Kim to −14.2% versus Cotes). For adults, the highest raw agreement for GLI was with Miller equations (94.7%), while for children it was with Kim equations (98.1%). Results were reclassified from abnormal to normal more frequently for younger adults, and for adult females, particularly when moving from Roca to GLI equations (30% of females versus 16% of males).The adoption of GLI TLCO reference equations in adults will result in altered interpretation depending on the equations previously used and to a greater extent in adult females. The effect on interpretation in children is less significant.Adoption of GLI TLCO reference equations in adults will result in altered interpretation depending on the equations previously used and to a greater extent in adult females. The effect on interpretation in children is less significant. http://bit.ly/3cmRzsY %U //www.qdcxjkg.com/content/erj/55/5/1901905.full.pdf