@article {Brazzale1901905，作者= {Brazzale，丹尼J.和Seccombe，利M.和威尔士，利亚姆和LANTERI，西莉亚J.和法拉，克劳德S.和Ruehland，沃伦R.}，标题= {采用的影响全球肺功能倡议一氧化碳转移因子}，体积的解释2017参考方程= {55}，数= {5}，elocation-ID = {1901905}，年= {2020}，DOI = {10.1183 / 13993003.01905-2019}，出版商= {欧洲呼吸学会}，188bet官网地址抽象= {最近公布的全球肺功能倡议（GLI）一氧化碳转移因子（TLCO）参考方程提供采用当前，不分年龄，适用广泛参考集的机会。The aim of this study was to document the effect of changing to GLI from commonly utilised reference equations on the interpretation of TLCO results.33 863 TLCO results (48\% female, 88\% Caucasian, n=930 aged \<18 years) from clinical pulmonary function laboratories within three Australian teaching hospitals were analysed. The lower limit of normal (LLN) and proportion of patients with a TLCO below this value were calculated using GLI and other commonly used reference equations.The average TLCO LLN for GLI was similar or lower than the other equations, with the largest difference seen for Crapo equations (median: -1.25, IQR: -1.64, -0.86 mmol{\textperiodcentered}min-1{\textperiodcentered}kPa-1). These differences resulted in altered rates of reduced TLCO for GLI particularly for adults (+1.9\% versus Miller to -27.6\% versus Crapo), more so than for children (-0.8\% versus Kim to -14.2\% versus Cotes). For adults, the highest raw agreement for GLI was with Miller equations (94.7\%), while for children it was with Kim equations (98.1\%). Results were reclassified from abnormal to normal more frequently for younger adults, and for adult females, particularly when moving from Roca to GLI equations (30\% of females versus 16\% of males).The adoption of GLI TLCO reference equations in adults will result in altered interpretation depending on the equations previously used and to a greater extent in adult females. The effect on interpretation in children is less significant.Adoption of GLI TLCO reference equations in adults will result in altered interpretation depending on the equations previously used and to a greater extent in adult females. The effect on interpretation in children is less significant. http://bit.ly/3cmRzsY}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/55/5/1901905}, eprint = {//www.qdcxjkg.com/content/55/5/1901905.full.pdf}, journal = {European Respiratory Journal} }