@article {Neder2000191，作者= {Neder，J.阿尔贝托和伯顿达尼洛蒂C.和了Nery，路易斯E.和Tan，C.万和Bourbeau，Jean和-O {\ textquoteright}唐奈，丹尼斯E.}，编辑={，}，标题=，elocation-ID = {2000191}，年= {2020}，DOI = {10.1183 / 13993003.00191-2020}，{出版商参考的评定劳力呼吸困难的强度期间增量周期测力甲帧} ={188bet官网地址欧洲呼吸学会}，抽象= {评估增量心肺运动试验（CPET）在呼吸困难的严重程度一直受到阻碍，缺乏参考值范围为工作率（WR）和通风（VE）的功能。这是为了循环特别相关，这负担过腿部肌肉导致腿discomfort.Reference的提高感觉测试模态范围基于呼吸困难百分位数（0 {\ textendash} 10 Borg评分）在标准化WRS和VE建立在275显然健康受试者年龄20 {\ textendash} 85（131人）。它们与记录在一个随机选择的{\ textquotedblleft}验证{\ textquotedblright}样品（N = 451，224名男性）的值进行比较。他们在正确揭示劳力性呼吸困难的严重程度有用的167个科目下调查慢性呼吸困难进行了测试（{\ textquotedblleft}测试样本{\ textquotedblright}）谁终止CPET由于腿部不适（86人）.ISO-WR和，以在较小程度上，异VE参考范围（第五{\ textendash} 25日，第25 {\ textendash}第50，50 {\ textendash} 75和第75 {\ textendash} 95百分位数）增加作为年龄的函数，是系统地高于妇女（p \ <0.01）。有在{\ textquotedblleft}参考{\ textquotedblright}和{\ textquotedblleft}验证{\ textquotedblright}样品（P \> 0.05）之间百分分布没有显著差异。 Submaximal dyspnoea-WR scores lied within the 75th{\textendash}95th or \>95th percentiles in 108/118 (91.5\%) subjects of the {\textquotedblleft}testing{\textquotedblright} sample who showed physiological abnormalities known to elicit exertional dyspnoea i.e., ventilatory inefficiency and/or critical inspiratory constraints. In contrast, dyspnoea scores typically lied in the 5th{\textendash}50th range in subjects without those abnormalities (p\<0.001).This frame of reference might prove useful to uncover the severity of exertional dyspnoea in subjects who otherwise would be labeled as {\textquotedblleft}non-dyspneic{\textquotedblright} while providing mechanistic insights into the genesis of this distressing symptom.FootnotesThis manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.Conflict of interest: Dr. NEDER has nothing to disclose.Conflict of interest: Dr. BERTON has nothing to disclose.Conflict of interest: Dr. NERY has nothing to disclose.Conflict of interest: Dr. O{\textquoteright}DONNELL has nothing to disclose.Conflict of interest: Dr. TAN reports grants from Canadian Respiratory Research Network , grants from AstraZeneca Canada Ltd, grants from Boehringer Ingelheim Canada Ltd, grants from GlaxoSmithKline Canada Ltd, grants from Novartis, grants from Canadian Institutes of Health Research , grants from Respiratory Health Network of the Fonds de la recherche en sant{\'e} du Qu{\'e}bec , grants from Merck, grants from Nycomed, grants from Pfizer Canada Ltd, from Theratechnologies, during the conduct of the study;.Conflict of interest: Dr. Bourbeau reports grants from CIHR, grants from Canadian Respiratory Research Network (CRRN), personal fees from Canadian Thoracic Society, personal fees from CHEST, grants from Foundation of the MUHC, grants from Aerocrine, grants and personal fees from AstraZeneca, grants and personal fees from Boehringer Ingelheim, grants and personal fees from Grifols, grants and personal fees from GlaxoSmithKline, grants and personal fees from Novartis, grants and personal fees from Trudell, outside the submitted work;.}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/early/2020/05/19/13993003.00191-2020}, eprint = {//www.qdcxjkg.com/content/early/2020/05/19/13993003.00191-2020.full.pdf}, journal = {European Respiratory Journal} }