TY - JOUR T1 - 合并症及对1590例COVID-19在中国的影响：一个全国性的分析JF - 欧洲呼吸杂志JO - EUR呼吸杂志DO - 10.1183 / 13993003.00547-2020 VL - 55 - 5 SP - 2000547 AU -关，卫杰盟 - 梁启超文华盟 - 赵易非盟 - 梁启超恒锐AU - 陈梓生AU - 李，易敏AU - 刘，小清AU - 陈茹-chong AU - 唐春利AU - 王滔AU - 欧，春全盟 - 李，李盟 - 陈，平欣AU - 桑，凌AU - 王，魏盟 - 李，建福AU - 李，蔡辰AU - 欧，李民AU - 诚，博AU - 熊，山盟 - 倪，郑毅AU - 翔杰AU - 胡，俞AU - 刘，雷盟 - 山，宏盟 - 雷春亮AU - 鹏，宜香AU - 伟，李AU - 刘雍AU - 胡，雅华盟 - 彭，彭AU - 王，建明AU - 刘霁杨盟 - 陈，钟AU - 李，刚AU - 郑，志坚AU - 秋，邵琴AU - 罗，捷盟 - 烨，常江AU - 朱邵勇AU - 诚，Lin-的凌AU - 野，冯AU - 李，施跃AU - 郑，金平AU - 张，诺富AU - 钟，南山AU - 他，建星A2 - ，Y1 - 2020年5月1日UR - //www.qdcxjkg.com/content/55/5/2000547.abstract N2 - 背景冠状病毒病2019（COVID-19）疫情发展迅速worldwide.Objective要通过分层的合并症status.Methods我们分析的数据来自1590例实验室确认的31个省住院患者从575家医院评价严重不良后果的风险，患者COVID-19/自治区/在中国大陆省级直辖市12月11日到2020年一月期间2019 31我们分析了复合终点，其中包括入院到重症监护病房，有创通气或死亡。The risk of reaching the composite end-points was compared according to the presence and number of comorbidities.Results The mean age was 48.9 years and 686 (42.7%) patients were female. Severe cases accounted for 16.0% of the study population. 131 (8.2%) patients reached the composite end-points. 399 (25.1%) reported having at least one comorbidity. The most prevalent comorbidity was hypertension (16.9%), followed by diabetes (8.2%). 130 (8.2%) patients reported having two or more comorbidities. After adjusting for age and smoking status, COPD (HR (95% CI) 2.681 (1.424–5.048)), diabetes (1.59 (1.03–2.45)), hypertension (1.58 (1.07–2.32)) and malignancy (3.50 (1.60–7.64)) were risk factors of reaching the composite end-points. The hazard ratio (95% CI) was 1.79 (1.16–2.77) among patients with at least one comorbidity and 2.59 (1.61–4.17) among patients with two or more comorbidities.Conclusion Among laboratory confirmed cases of COVID-19, patients with any comorbidity yielded poorer clinical outcomes than those without. A greater number of comorbidities also correlated with poorer clinical outcomes.The presence and number of comorbidities predict clinical outcomes of COVID-19 http://bit.ly/3b9ibw5 ER -