%0期刊论文%一关,卫杰%阿亮,文华%A照,易%阿亮,恒锐%阿陈,梓盛%A李易敏%A柳,Xiao-清%阿陈,汝庄%A唐春利%A王滔%A欧,春全%A锂,李%阿陈,平欣%A桑,凌%A王,魏%一立,建辅%A李,蔡辰%A欧,利民%阿城,博%A熊,山%A倪,郑毅%阿翔,捷%A胡,A刘裕%雷%A山,洪%阿磊,纯良%阿朋,宜香%阿伟,A刘丽%,雍%A胡锦涛,雅华%A彭,彭%A王,建明%A刘霁阳%阿陈,钟%A李岗%阿正,志坚%A秋,邵琴%罗,捷%爷,常江%A朱,邵勇%阿城,林龄%A烨,冯%A李,施跃%阿正,金平%A章,傩福%阿忠,南山%A他,建星%A,%T合并症并用COVID-19在中国其对1590名患者的影响:在全国范围内分析%d 2020%R 10.1183 / 13993003.00547-2020%Ĵ欧洲呼吸杂志%P 2000547%V 55%N 5%X背景冠状病2019(COVID-19)outbreak的快速发展worldwide.Objective要通过分层的合并症status.Methods我们分析的数据来自1590例实验室确认的31个省/自治区/直辖市省级整个住院的病人从医院575评估严重不良后果的风险,患者COVID-1912月11日到2020年一月期间2019 31中国大陆我们分析了复合终点,其中包括入院到重症监护病房,有创通气或死亡。The risk of reaching the composite end-points was compared according to the presence and number of comorbidities.Results The mean age was 48.9 years and 686 (42.7%) patients were female. Severe cases accounted for 16.0% of the study population. 131 (8.2%) patients reached the composite end-points. 399 (25.1%) reported having at least one comorbidity. The most prevalent comorbidity was hypertension (16.9%), followed by diabetes (8.2%). 130 (8.2%) patients reported having two or more comorbidities. After adjusting for age and smoking status, COPD (HR (95% CI) 2.681 (1.424–5.048)), diabetes (1.59 (1.03–2.45)), hypertension (1.58 (1.07–2.32)) and malignancy (3.50 (1.60–7.64)) were risk factors of reaching the composite end-points. The hazard ratio (95% CI) was 1.79 (1.16–2.77) among patients with at least one comorbidity and 2.59 (1.61–4.17) among patients with two or more comorbidities.Conclusion Among laboratory confirmed cases of COVID-19, patients with any comorbidity yielded poorer clinical outcomes than those without. A greater number of comorbidities also correlated with poorer clinical outcomes.The presence and number of comorbidities predict clinical outcomes of COVID-19 http://bit.ly/3b9ibw5 %U //www.qdcxjkg.com/content/erj/55/5/2000547.full.pdf