@article {Pengo1901945，作者= {彭格，Martino的F.和Soranna，达维德和Giontella，Alice和Perger，ELISA和Mattaliano，保拉和施瓦茨，以斯帖艾琳和Lombardi，卡罗莱纳州和比洛，和的Grzegorz赞邦，安东和Steier，约尔格和帕拉蒂，詹弗兰科和Minuz，彼得和Fava的，克里斯蒂}，标题= {阻塞性睡眠呼吸暂停的治疗和血压：其表型预测的响应？系统回顾和荟萃分析}，体积= {} 55，数= {5}，elocation-ID = {1901945}，年= {} 2020，DOI = {10.1183 / 13993003.01945-2019}，出版商= {欧洲呼吸社会}，抽象= {治疗阻塞性睡眠呼吸暂停（OSA）与持续气道正压（CPAP）或下颌前移装置（MADS）与（BP）血压降低相关联;然而，整体效果是有限的。该系统评价和随机对照试验（RCT）比较对BP这样的治疗效果的荟萃分析的目的是确定与特定搜索字词三个不同的数据库进行了回应谁最好treatment.The文章搜索亚组患者和选择标准。从2289篇，我们包括随机对照试验68相比CPAP或MADS与被动或主动治疗。When all the studies were pooled together, CPAP and MADs were associated with a mean BP reduction of -2.09 (95\% CI -2.78{\textendash} -1.40) mmHg for systolic BP and -1.92 (95\% CI -2.40{\textendash} -1.43) mmHg for diastolic BP and -1.27 (95\% CI -2.34{\textendash} -0.20) mmHg for systolic BP and -1.11 (95\% CI -1.82{\textendash} -0.41) mmHg for diastolic BP, respectively. The subgroups of patients who showed a greater response were those aged \<60 years (systolic BP -2.93 mmHg), with uncontrolled BP at baseline (systolic BP -4.14 mmHg) and with severe oxygen desaturations (minimum arterial oxygen saturation measured by pulse oximetry \<77\%) at baseline (24-h systolic BP -7.57 mmHg).Although this meta-analysis shows that the expected reduction of BP by CPAP/MADs is modest, it identifies specific characteristics that may predict a pronounced benefit from CPAP in terms of BP control. These findings should be interpreted with caution; however, they are particularly important in identifying potential phenotypes associated with BP reduction in patients treated for OSA.This study identified age, blood pressure levels before treatment and hypoxic burden expressed by the minimum desaturation as potential predictors of blood pressure reduction in patients treated for obstructive sleep apnoea http://bit.ly/31LdrJA}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/55/5/1901945}, eprint = {//www.qdcxjkg.com/content/55/5/1901945.full.pdf}, journal = {European Respiratory Journal} }