TY - T1的稳定和进步的IPF患者循环RNA差异JF -欧洲呼吸杂志》乔和J - 10.1183/13993003.02058 -2019欧元SP - 1902058 AU Clynick Britt AU -乔,海伦·e . AU -科尔特大学Tamera J . AU - Glaspole伊恩·n . AU - Grainge克里斯托弗AU -霍普金斯,彼得•硕士AU -雷诺兹保罗n . AU -查普曼,莎莉AU -沃尔特斯,e·海顿盟——Zappala克里斯托弗AU -基尔,Gregory j . AU -库珀,温迪·a . AU - Mahar安娜贝拉m . AU -埃利斯,萨曼莎AU -吴作栋,妮可·s . AU -波罗的海斯维特拉娜AU -瑞恩,玛丽莎AU - Tan,恐龙文学士学位盟——MoodleyN2 -特发性肺纤维化(Idiopathic pulmonary fibrosis, IPF)是一种以肺功能进行性下降为特征的慢性疾病。[1]下降的速度各不相同，一些患者在较长时间内保持稳定，而另一些患者[1]迅速进展。该病的可变进展使得阐明IPF的起始和进展的致病途径变得困难。高通量基因表达分析的进展使我们对疾病生物学和预后基因特征的理解有所改善。我们假设，与健康对照组相比，IPF具有独特的循环转录谱，稳定和进展性疾病之间的额外差异可能与疾病发病机制有关。脚注本手稿最近已被接受发表在欧洲呼吸杂志。在我们的制作团队进行编辑和排版之前，它以接受的形式在这里发表。在这些生产过程完成后，作者已经批准了结果的证明，文章将移动到最新一期的ERJ在线。请打开或下载PDF以查看本文。Conflict of interest: Miss Clynick has nothing to disclose.Conflict of interest: Dr. Jo has nothing to disclose.Conflict of interest: Dr. Corte has nothing to disclose.Conflict of interest: Dr. Glaspole has nothing to disclose.Conflict of interest: Dr. Grainge has nothing to disclose.Conflict of interest: Dr. Hopkins has nothing to disclose.Conflict of interest: Dr. Reynolds has nothing to disclose.Conflict of interest: Dr. Chapman has nothing to disclose.Conflict of interest: Dr. Walters has nothing to disclose.Conflict of interest: Dr. Zappala has nothing to disclose.Conflict of interest: Dr. Keir has nothing to disclose.Conflict of interest: Dr. Cooper has nothing to disclose.Conflict of interest: Dr. Mahar has nothing to disclose.Conflict of interest: Dr. Ellis has nothing to disclose.Conflict of interest: Dr. Goh has nothing to disclose.Conflict of interest: Dr. Baltic has nothing to disclose.Conflict of interest: Miss Ryan has nothing to disclose.Conflict of interest: Dr. Tan has nothing to disclose.Conflict of interest: Dr. Moodley has nothing to disclose. ER -