TY - JOUR T1 -胸部CT上可能常见的间质性肺炎模式:是否足以诊断特发性肺纤维化?JF -欧洲呼吸杂志》乔和J - 10.1183/13993003.02465 -2018欧元六世- 55 - 4 SP - 1802465 AU Fukihara 6月盟,Kondoh Yasuhiro AU -布朗,凯文·k . AU -木村,名叫Tomoki AU - Kataoka Kensuke盟——松田Toshiaki盟——Yamano Yasuhiko盟——铃木Atsushi盟——古河道,Taiki盟——Sumikawa AU -高桥弘满Osamu AU - Johkoh, Takeshi AU - Tanaka, Tomonori AU - Fukuoka, Junya AU - Hashimoto, Naozumi AU - Hasegawa, Yoshinori Y1 - 2020/04/01 UR - //www.qdcxjkg.com/content/55/4/1802465.abstract N2 -最近的研究表明，在特发性间质性肺炎(IIP)患者中，胸部计算机断层扫描(CT)上可能常见的间质性肺炎(UIP)模式足以诊断特发性肺纤维化(IPF)而无需组织病理学。我们回顾性比较了IIP患者首次急性加重(AE)的预后和时间，在初始胸部CT上有UIP和可能的UIP模式。160名具有UIP模式的IIP患者和242名可能具有UIP模式的IIP患者被确定。可能的UIP模式与较长生存时间独立相关(校正风险比0.713,95% CI 0.536-0.950;p=0.021)和时间到第一次AE(校正风险比0.580,95% CI 0.389-0.866;p = 0.008)。在接受手术肺活检的可能UIP模式的受试者中，组织病理学UIP模式的概率为83%。经过多学科讨论和纳入纵向行为，66%的病例诊断为IPF。在IPF患者中，生存时间和发生首次AE的时间与CT类型无关。 Among subjects with a probable UIP pattern, compared to non-IPF patients, survival time and time to first AE were shorter in IPF patients.In conclusion, IIP patients with a probable UIP pattern on initial chest CT had a better prognosis and longer time to first AE than those with a UIP pattern. However, when baseline data and longitudinal behaviour provided a final diagnosis of IPF, CT pattern was not associated with these outcomes. This suggests diagnostic heterogeneity among patients with a probable UIP pattern.Except when the final diagnosis is IPF, idiopathic interstitial pneumonia (IIP) patients with a probable usual interstitial pneumonia (UIP) pattern on chest CT have a longer survival time and time to first acute exacerbation than those with a UIP pattern http://bit.ly/2FOJa2F ER -