@article {Fukihara1802465, author = {Fukihara, Jun和Kondoh, Yasuhiro和Brown, Kevin K.和Kimura, Tomoki和Kataoka, Kensuke和Matsuda, Toshiaki和Yamano, Yasuhiko和Suzuki, Atsushi和Furukawa, Taiki和Sumikawa, Hiromitsu和Takahashi, Osamu和Johkoh, Takeshi和Tanaka, Tomonori和福冈，Junya和桥本，Naozumi和Hasegawa, Yoshinori}， title ={胸部CT上可能的常见间质性肺炎模式:是否足以诊断特发性肺纤维化?}， volume = {55}， number = {4}， elocation-id = {1802465}， year = {2020}， doi = {10.1183/13993003.02465-2018}， publisher = {188bet官网地址European Respiratory Society}， abstract = {胸部计算机断层扫描(CT)上可能常见的间质性肺炎(UIP)模式足以诊断特发性肺纤维化(IPF)而无需组织病理学。我们回顾性比较了IIP患者首次急性加重(AE)的预后和时间，在初始胸部CT上有UIP和可能的UIP模式。160名具有UIP模式的IIP患者和242名可能具有UIP模式的IIP患者被确定。可能的UIP模式与较长的生存时间独立相关(调整后的风险比0.713,95% CI 0.536, 0.950;p=0.021)和时间到第一次AE(调整风险比0.580,95\% CI 0.389{\textendash}0.866;p = 0.008)。在接受手术肺活检的可能UIP模式的受试者中，组织病理学UIP模式的概率为83%。经过多学科讨论和纳入纵向行为，66%的病例诊断为IPF。在IPF患者中，生存时间和发生首次AE的时间与CT类型无关。 Among subjects with a probable UIP pattern, compared to non-IPF patients, survival time and time to first AE were shorter in IPF patients.In conclusion, IIP patients with a probable UIP pattern on initial chest CT had a better prognosis and longer time to first AE than those with a UIP pattern. However, when baseline data and longitudinal behaviour provided a final diagnosis of IPF, CT pattern was not associated with these outcomes. This suggests diagnostic heterogeneity among patients with a probable UIP pattern.Except when the final diagnosis is IPF, idiopathic interstitial pneumonia (IIP) patients with a probable usual interstitial pneumonia (UIP) pattern on chest CT have a longer survival time and time to first acute exacerbation than those with a UIP pattern http://bit.ly/2FOJa2F}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/55/4/1802465}, eprint = {//www.qdcxjkg.com/content/55/4/1802465.full.pdf}, journal = {European Respiratory Journal} }