TY - T1的棱镜的全球意义:how data from low- and middle-income countries link physiology to inflammation JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.00184-2020 VL - 55 IS - 4 SP - 2000184 AU - Jackson, Peter AU - Siddharthan, Trishul Y1 - 2020/04/01 UR - //www.qdcxjkg.com/content/55/4/2000184.abstract N2 - We read with great interest the article by Wijnant et al. [1] in a recent issue of European Respiratory Journal investigating the longitudinal outcomes of patients with preserved ratio impaired spirometry (PRISm) in the Rotterdam cohort. PRISm is a subject of increased investigation as it is associated with respiratory symptoms, cardiovascular disease, metabolic syndrome and, quite clearly in the recent study, increased mortality [1–3]. While there have been numerous studies examining outcomes related to PRISm in high-income countries (HICs), few studies have assessed the clinical significance of this spirometric finding in low- and middle-income countries (LMICs).Does the high rate and unique risk factors of preserved ratio impaired spirometry in low- and middle-income countries have something to teach us about the physiology of this highly prevalent pattern? http://bit.ly/2SsQjeG ER -