TY - T1的运动不耐受在慢性血栓栓塞肺动脉高压肺血管成形术后摩根富林明-欧洲呼吸杂志》乔和J - 10.1183/13993003.01982 -2019欧元SP - 1901982 AU -菊池,花子盟——Goda亚由美盟,竹内薰盟——Inami Takumi盟——Kohno隆非盟-坂田,Konomi AU - Soejima,佐藤恭子，Toru Y1 - 20/01/01 UR - //www.qdcxjkg.com/content/early/2020/04/01/13993003.01982-2019.abstract N2 -背景运动性肺动脉高压常见于慢性血栓栓塞性肺动脉高压患者，这些患者在运动时呼吸短促，尽管肺动脉正常，但运动能力下降压力在休息;然而，运动性肺动脉高压与运动能力之间的关系尚不清楚。在这里，我们的目的是确定运动性肺动脉高压是否与慢性血栓栓塞性肺动脉高压患者在肺球囊血管成形术(BPA)后静止血流动力学正常的运动能力和通气效率相关。双酚a治疗慢性血栓栓塞性肺动脉高压患者249例(年龄63±14岁;静息时平均肺动脉压(<25 mmHg)和楔形压(≤15 mmHg)正常的患者，用右心导管进行心肺运动测试。将运动时的平均肺动脉压-心输出量(mapp - co)绘制为多点图。运动性肺动脉高压的定义是mapp - co斜率大于3。结果休息时，运动性肺动脉高压组(n=116)肺血管阻力明显高于非运动性肺动脉高压组(n=133)。 Lower peak oxygen consumption (13.5±3.8 versus 16.6±4.7 mL·min−1·kg−1, p<0.001) was observed in the former group. The mPAP-CO slope was negatively correlated with the peak oxygen consumption (r=−0.45, p<0.001) and positively correlated with the minute ventilation versus carbon dioxide output slope (r=0.39, p<0.001).Conclusions Impaired exercise capacity and ventilatory efficiency were observed in patients with chronic thromboembolic pulmonary hypertension who had normalised pulmonary artery pressure at rest but exercise pulmonary hypertension.FootnotesThis manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.Conflict of interest: Dr. Kikuchi has nothing to disclose.Conflict of interest: Dr. Goda has nothing to disclose.Conflict of interest: Dr. Takeuchi has nothing to disclose.Conflict of interest: Dr. Inami has nothing to disclose.Conflict of interest: Dr. Kohno has nothing to disclose.Conflict of interest: Dr. Sakata has nothing to disclose.Conflict of interest: Dr. Soejima has nothing to disclose.Conflict of interest: Dr. Satoh has nothing to disclose. ER -