TY -的T1 -消失的船只住所肺disease: a role for VEGFR2 JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.00326-2020 VL - 55 IS - 4 SP - 2000326 AU - Botros, Liza AU - Vonk Noordegraaf, Anton AU - Aman, Jurjan Y1 - 2020/04/01 UR - //www.qdcxjkg.com/content/55/4/2000326.abstract N2 - There is growing recognition for the involvement of blood vessels in pulmonary diseases beyond the classical scope of pulmonary vascular medicine. As an example, reports have described a vascular phenotype of COPD, or have proposed a vanishing pulmonary capillary syndrome to underly emphysema [1, 2]. Although the number of clinical and epidemiological studies supporting such a vascular hypothesis of pulmonary disease is steadily growing, biological underpinning in clinical studies remains to be provided.VEGFR2 has a pivotal and specific role in vascular homeostasis and VEGFR2 mutations provide robust clinical evidence for direct involvement of a disturbed vasculature in a wide variety of lung diseases http://bit.ly/383ixTb ER -