ty -jour t1-校际高加索儿童的多次呼吸冲洗结果的规范数据JF-欧洲呼吸杂志- Latzin, Philipp AU - Jensen, Renee AU - Stahl, Mirjam AU - Harper, Alana AU - Yammine, Sophie AU - Usemann, Jakob AU - Foong, Rachel E. AU - Spycher, Ben AU - Hall, Graham L. AU -歌手，Florian au -Stanojevic，Sanja au-购物中心，Marcus A. Au -Ratjen，Felix au -Ramsey -Ramsey，Kathryn A. Y1- 2020/04/01 Ur -http://erj.ersjourj.ersjournals.com/content/55/55/55/4/1901302.Abstract N2-背景多重呼吸氮冲洗（N2MBW）技术越来越多地用于评估肺部疾病校际儿童的通风不均匀程度。但是，目前尚无健康儿童的参考值。这项研究的目的是在健康的高加索学龄儿童中产生N2MBW结果的参考值。从四个经验丰富的中心收集了来自健康的高加索学龄儿童6至18岁的健康学龄儿童的方法N2MBW数据。使用超声流量计（Exhalyzer D，Eco Medic AG，Duernten，Switzerland）进行测量，并使用商业软件（Spiroware版本3.2.1，Eco Medic AG）进行分析。以2.5％（LCI2.5％）和最初氮浓度的5％（LCI2.5％）为2.5％（LCI2.5％），为肺清除指数（LCI）产生正常（ULN）的规范值和上限（ULN）（LCI）（M1/M0和M1/M0和M1/M0和M1/M0）和5％（LCI5％）（LCI5％）M2/M0）。生成了用于功能剩余能力的预测方程（FRC）。分析分析使用了485个从6至18岁的健康高加索儿童进行的485次试验。 While LCI increased with age, this increase was negligible (0.04 units·year–1 for LCI2.5%) and therefore fixed ULN were defined for this age group. These limits were 7.91 for LCI2.5%, 5.73 for LCI5%, 1.75 for M1/M0 and 6.15 for M2/M0, respectively. Height and weight were found to be independent predictors of FRC.Conclusion We report reference values for N2MBW outcomes measured on a commercially available ultrasonic flowmeter device (Exhalyzer D, Eco Medics AG) in healthy school-aged children to allow accurate interpretation of ventilation distribution outcomes and FRC in children with lung disease.This study provides reference values for nitrogen multiple breath washout outcomes in healthy Caucasian children from 6 to 18 years old, measured with a commercially available device http://bit.ly/2rsab8v ER -