RT期刊文章SR电子T1规范数据为多个呼吸冲刷的结果在学龄白人孩子摩根富林明欧洲呼吸杂志乔和J FD欧元欧洲呼吸学会SP 1901302 10.1183/13993003.01302 -2019签证官55是4 A1 Anagnostopoulou, Pinelopi A1 Latzin,菲利普A1詹森,蕾妮A1斯塔尔,Mirjam A1哈珀,188bet官网地址Alana A1 Yammine Sophie A1 Usemann Jakob A1 Foong Rachel E. A1 Spycher Ben A1 Hall Graham L. A1 Singer Florian A1 Stanojevic Sanja A1 Mall Marcus A. A1 Ratjen Felix A1 RamseyKathryn A. YR 2020 UL //www.qdcxjkg.com/content/55/4/1901302.abstract AB背景多重呼吸氮洗脱(N2MBW)技术越来越多地被用于评估学龄期肺部疾病患儿的通气不均匀程度。但是，目前还没有健康儿童的参考值。本研究的目的是为一组健康高加索学龄儿童的N2MBW结果提供参考价值。方法收集4个有经验中心6 ~ 18岁健康白种人学龄儿童的N2MBW数据。使用超声波流量计(Exhalyzer D, Eco Medics AG, Duernten, Switzerland)进行测量，并使用商业软件(spirroware version 3.2.1, Eco Medics AG)进行分析。肺清除率指数(LCI)在初始氮浓度的2.5% (LCI2.5%)和5% (LCI5%)以及矩比(M1/M0和M2/M0)时生成标准值和正常上限(ULN)。建立了功能剩余容量(FRC)的预测方程。结果分析使用了来自180名6至18岁健康高加索儿童的485项试验。 While LCI increased with age, this increase was negligible (0.04 units·year–1 for LCI2.5%) and therefore fixed ULN were defined for this age group. These limits were 7.91 for LCI2.5%, 5.73 for LCI5%, 1.75 for M1/M0 and 6.15 for M2/M0, respectively. Height and weight were found to be independent predictors of FRC.Conclusion We report reference values for N2MBW outcomes measured on a commercially available ultrasonic flowmeter device (Exhalyzer D, Eco Medics AG) in healthy school-aged children to allow accurate interpretation of ventilation distribution outcomes and FRC in children with lung disease.This study provides reference values for nitrogen multiple breath washout outcomes in healthy Caucasian children from 6 to 18 years old, measured with a commercially available device http://bit.ly/2rsab8v