TY - Jour T1 - 学校老年人儿童多呼吸冲洗结果的规范数据JF - 欧洲呼吸期刊Jo - Eur Respir J Do - 10.1183 / 13993003.01302-2019 VL - 55是 - 4 SP - 1901302 Au - Anagnostopoulou，Pinelopi Au- Latzin，Philipp Au - Jensen，Renee Au - Stahl，Mirjam Au - Harper，Alana Au - Yammine，Sophie Au - Usemann，Jakob Au - Foong，Rachel E. Au - Spycher，Ben Au - Hall，Graham L. Au -歌手，Florian Au - Stanojevic，Sanja Au - Mall，Marcus A. Au - Ratjen，Felix Au - Ramsey，Kathryn A. Y1 - 2020/04/01 UR - //www.qdcxjkg.com/content/55/4 / 1901302.Abstract n2 - 背景技术多呼吸氮气冲洗（N2MBW）技术越来越多地用于评估肺病学龄儿童的通风越突起程度。但是，目前无法获得健康儿童的参考价值。本研究的目的是为健康高加索学龄儿童队列的N2MBW成果产生参考价值。从4个经验丰富的中心收集来自6至18岁的健康高加索学龄儿童的N2MBW数据。使用超声波流量计进行测量（Extalyzer D，Eco Medics AG，​​Duernten，瑞士），并用商业软件（Spiroware 3.2.1，Eco Medics AG）进行分析。为肺部间隙指数（LCI）产生正常（ULN）的规范性值和上限，以2.5％（LCI2.5％）和初始氮浓度的5％（LCI5％）和矩比率（M1 / M0和m2 / m0）。为功能残留能力（FRC）产生预测方程。结果分析使用了从6至18岁的180名健康高加索儿童的485名试验。 While LCI increased with age, this increase was negligible (0.04 units·year–1 for LCI2.5%) and therefore fixed ULN were defined for this age group. These limits were 7.91 for LCI2.5%, 5.73 for LCI5%, 1.75 for M1/M0 and 6.15 for M2/M0, respectively. Height and weight were found to be independent predictors of FRC.Conclusion We report reference values for N2MBW outcomes measured on a commercially available ultrasonic flowmeter device (Exhalyzer D, Eco Medics AG) in healthy school-aged children to allow accurate interpretation of ventilation distribution outcomes and FRC in children with lung disease.This study provides reference values for nitrogen multiple breath washout outcomes in healthy Caucasian children from 6 to 18 years old, measured with a commercially available device http://bit.ly/2rsab8v ER -