Ty -jour t1-特发性肺纤维化的急性加剧：国际调查和协调呼吁JF-欧洲呼吸杂志-Polke，Markus au -Walsh，Simon L.F. Au -Krisam，Johannes au -Collard，Harold R. Au -Chaudhuri -Chaudhuri，Nazia au -avdeev，Sergey au -au -behr -behr，jürgenau -calligaro -calligaro，Gregory au -corte -corte -corte -corte -corte -t​​amera au -flaherty au -flaherty au -flaherty au -flaherty，Kevin Au -Funke -Chambour，Manuela au -Kolb，Martin au -Kondoh，Yasuhiro au -Maher -Maher，Toby M. Au -Molina Molina -Molina Molina，Maria au -Maria au -Morais，Antonio au -Moor，Moor，Catharina C. Au -Morisset，Julie au au au au au au -julie au au au au au au au au au。-Pereira，Carlos au -Quadrelli，Silvia au -Selman，Moises Au -Tzouvelekis，Argyrios au -Valenzuela -Valenzuela，Claudia au -Vancheri，Carlo au -vicens -Zygmunt，Vicens -Zygmunt，Vanesa au -Wälscher，Joulia -julia -julia -wiy auts autssMARLIES AU -COTTIN，VINCENT AU -BENDSTRUP，ELISABETH Y1-2020/04/01 UR -http：//www.qdcxjkg.com/content/55/4/4/1901760.Abstract N2-特发性肺纤维化（AE-IPF）的急性加重是IPF的致命并发症。没有针对AE-IPF管理的重点国际指南。这项国际调查的目的是评估AE-IPF的预防，诊断和治疗策略的全球变异性。具有ILD专业知识的Pulonologists被邀请参加由国际专家小组设计的调查。509名来自66个国家的肺科医生作出了回应。发现管理AE-IPF的方法的显着地理变异性。常见的预防措施包括抗纤维化药物和疫苗接种。诊断差异在使用Krebs Von den Lungen-6和病毒测试方面最为明显，而高分辨率计算机断层扫描，脑脂肪尿素肽和D-二聚体通常被应用。 High-dose steroids are widely administered (94%); the use of other immunosuppressant and treatment strategies is highly variable. Very few (4%) responders never use immunosuppression. Antifibrotic treatments are initiated during AE-IPF by 67%. Invasive ventilation or extracorporeal membrane oxygenation are mainly used as a bridge to transplantation. Most physicians educate patients comprehensively on the severity of AE-IPF (82%) and consider palliative care (64%).Approaches to the prevention, diagnosis and treatment of AE-IPF vary worldwide. Global trials and guidelines to improve the prognosis of AE-IPF are needed.Lack of focussed international guidelines for management of acute exacerbation of IPF results in global variability in prevention, diagnosis and treatment strategies. Global trials are urgently needed to inform international specific guidelines for AE-IPF. http://bit.ly/3a8FB5i ER -