TY - T1的实验性呼吸困难妨碍运动和认知:一个随机试验JF -欧洲呼吸杂志》乔和J - 10.1183/13993003.00054 -2020欧元SP - 2000054 AU Lawi大卫盟——Dupuis Elise-Lozeron AU -贝瑞,格里高利盟——Allali Gilles盟——Similowski托马斯AU -阿德勒,丹Y1 - 2020/01/01 UR - //www.qdcxjkg.com/content/early/2020/03/26/13993003.00054 - 2020. -抽象N2 -背景慢性呼吸道疾病是与认知功能障碍有关,但呼吸困难本身是否对认知产生负面影响还没有被证明。皮质网络参与主体体验呼吸困难也激活在其他任务要求认知输入和可能引发的负面影响通过互相干扰。这个交叉随机试验方法研究实验性诱导呼吸困难是否会对运动和认知功能产生负面影响40健康的成年人。交叉条件卸载呼吸或呼吸使用吸气阈载荷加载。评估运动,参与者被评估的时间去测试。认知功能被分类和音位的言语流畅性测试评估,跟踪使测试A和B(执行功能),测试代码与WAIS-IV(处理速度),并通过直接和间接数字广度(工作记忆)。结果平均执行时间和时差去呼吸测试之间的卸载和加载−0.752秒(1.012−−0.492;术中,0.001)。执行功能、加工速度和工作记忆表现的更好在卸载呼吸,特别是对于主题开始第一次呼吸与加载条件。结论我们的数据表明,呼吸道阈值加载引起呼吸困难有一个主要的健康成年人对运动和认知功能的影响。FootnotesThis手稿最近发表在《欧洲呼吸杂志》上。这里发表周全之前接受的形式排版,我们的生产团队。这些生产过程完成后,作者已经批准结果证明,本文将最新一期的ERJ在线。请打开或下载PDF查看这篇文章。Conflict of interest: Dr. Lawi has nothing to disclose.Conflict of interest: Dr. Dupuis-Lozeron has nothing to disclose.Conflict of interest: Dr. Berra has nothing to disclose.Conflict of interest: Dr. Allali has nothing to disclose.Conflict of interest: Dr. SIMILOWSKI reports personal fees from AstraZeneca France, personal fees from Boerhinger Ingelheim France, personal fees from GSK France, personal fees and non-financial support from Novartis France, personal fees from TEVA France, personal fees from Chiesi France, personal fees from Lungpacer Inc, personal fees from ADEP Assistance, grants from Air Liquide Medical Systems, outside the submitted work.Conflict of interest: Dr. Adler reports grants from The Geneva Pulmonary League, during the conduct of the study. ER -