PT -期刊文章盟Yasemin Turk盟威利Theel AU -阿斯特丽德·范·Huisstede盟Gert-Jan m . van de Geijn AU -欧文Birnie盟Pieter s Hiemstra AU -雅各布k是AU -基督教Taube盟Gert-Jan Braunstahl TI -高强度的短期和长期影响肺康复计划在肥胖患者哮喘:一项随机对照试验的援助- 10.1183/13993003.01820 -2019 DP - 2020年1月01 TA -欧洲呼吸杂志PG - 1901820 4099 - //www.qdcxjkg.com/content/early/2020/03/17/13993003.01820 - 2019. -短4100 - //www.qdcxjkg.com/content/early/2020/03/17/13993003.01820 - 2019. -完整的AB -目的确定一个高强度的短期和长期影响肺康复(PR)程序控制哮喘,身体成分,肥胖哮喘患者的肺功能和运动能力。方法患者肥胖(体重指数≥30公斤·m−2)和次优控制哮喘(哮喘控制问卷(ACQ)≥0.75)被随机分配给一个3个月肺康复计划(PR),肺康复计划使用一个基于互联网的自我管理支持程序(PR + SMS)或常规治疗。公关项目包括高强度间歇训练、营养干预和心理小组会议。常规治疗组的患者被建议减肥和锻炼。主要的结果之间的差异变化ACQ倾向和公关+短信后3个月。总随访12个月。结果34例患者纳入研究(14倾向,9公关+短信,11控制)。相比,患者在常规治疗,患者只公关组在体重指数显著降低,显著改善哮喘控制、运动能力和有氧能力后3个月。这些改进持续12个月的随访期间。之间没有区别ACQ公关+短信和公关只观察组。但是,短信的用户程序相比有显著降低BMI后12个月主题倾向组。Conclusion A high intensity pulmonary rehabilitation program provides sustained improvements in asthma control, body composition and exercise capacity in obese asthmatics that are not optimally controlled and, therefore, should be considered in the treatment of these patients.FootnotesThis manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.Conflict of interest: Dr. Türk reports grants from GSK, grants from TEVA, grants from Novartis, grants from Chiesi, during the conduct of the study.Conflict of interest: W. Theel has nothing to discloseConflict of interest: Dr. van Huisstede has nothing to disclose.Conflict of interest: Dr. van de Geijn reports personal fees and non-financial support from Beckman Coulter, outside the submitted work.Conflict of interest: Dr. Birnie has nothing to disclose.Conflict of interest: Dr. Hiemstra has nothing to disclose.Conflict of interest: Dr. Sont has nothing to disclose.Conflict of interest: Dr. Taube has nothing to disclose.Conflict of interest: Dr. Braunstahl reports grants from GSK, grants from Teva, grants from Novartis, grants from Chiesi, during the conduct of the study; personal fees from ALK Abello, personal fees from GSK, personal fees from AstraZeneca, personal fees from Sanofi, personal fees from Chiesi, personal fees from Novartis, outside the submitted work.