TY -的T1 -结果的“早期”慢性阻塞性肺病for interventional studies JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.02380-2019 VL - 55 IS - 3 SP - 1902380 AU - Rennard, Stephen I. Y1 - 2020/03/01 UR - //www.qdcxjkg.com/content/55/3/1902380.abstract N2 - The recent paper by Çolak et al. [1] and colleagues adds to the growing body of information relating to early COPD. The study confirms the importance of symptoms among individuals prior to meeting the arbitrary threshold of forced expiratory volume in 1 s (FEV1) to forced vital capacity ratio <0.7, and that these individuals are at risk for serious morbidity and mortality. Importantly, this is demonstrated in a population-based sample. The authors clearly address the difficulty in distinguishing “early” from “mild” COPD, but have included younger individuals, which suggests that “early” disease is present in many.Data presented in the recent study by Çolak and co-workers permit estimates of trials to alter natural history of COPD using endpoints other than FEV1 http://bit.ly/2sIxMSB ER -