PT -期刊文章盟Bomanji贾姆希盟,Sharma Rajnish AU -米塔尔,Bhagwant r . AU - Gambhir桑杰盟——Qureshy Ahmad盟的女王,、非盟第一部门,戴安娜盟——Sathekge迈克AU -沃斯,Mariza AU - Sobic Saranovic, Dragana盟——Pusuwan Pawana AU -曼,维拉盟——Vinjamuri索班盟——Zumla Alimuddin AU -帕斯卡,托马斯。注意:TI - PET / CT特点的肺外结核临床表现:横断面观察<一口> 18 < /一口> F-FDG成像研究在六个国家援助- 10.1183/13993003.01959 -2019 DP - 2020年2月01 TA -欧洲呼吸杂志》第六PG - 1901959 - 55 IP - 2 4099 - //www.qdcxjkg.com/content/55/2/1901959.short 4100 - //www.qdcxjkg.com/content/55/2/1901959.full所以欧元和J2020 2月01;55 AB -背景肺外结核(EPTB)病例的巨大全球负担中有很大一部分是经验治疗的,没有对疾病部位和多器官疾病累及程度的准确定义。摘要应用2-脱氧-2-(氟-18)氟-d-葡萄糖(18F-FDG)正电子发射断层显像(PET)在结核病诊断中的应用,是一种有效的疾病定位和疾病范围的显像技术。方法我们对印度、巴基斯坦、泰国、南非、塞尔维亚和孟加拉国等6个国家的8个中心的hiv阴性成人患者进行了一项新的临床诊断EPTB的研究,以评估首次发病时的疾病程度和常见部位。两周内进行18F-FDG PET/ CT扫描。结果358例EPTB患者(女189例;169名男性)被招募超过45个月,年龄范围18-83岁(女性平均30岁;男性平均38岁)。358名患者(183名女性,167名男性)中有350人(98%)的扫描结果为阳性。在350人当中,有118人(33.7%)有单一肺外病变,而在350人当中,有232人(66.3%)有多个肺外病变(器官)。 Lymph nodes, skeleton, pleura and brain were common sites. 100 (28%) out of 358 EPTB patients had 18F-FDG PET/CT-positive sites in the lung. 110 patients were 18F-FDG PET/CT-positive in more body sites than were noted clinically at first presentation and 160 patients had the same number of positive body sites.Interpretation 18F-FDG PET/CT scan has potential for further elucidating the spectrum of disease, pathogenesis of EPTB and monitoring the effects of treatment on active lesions over time, and requires longitudinal cohort studies, twinned with biopsy and molecular studies.18F-FDG PET/CT can localise EPTB disease sites not clinically detected. It may serve a useful tool for research studies defining pathogenetic mechanisms and cure, relapse and recurrence. http://bit.ly/2CKSH9a