@article {Bomanji1901959作者= {Bomanji贾姆希,沙玛,Rajnish和米塔尔,Bhagwant r . Gambhir,桑杰,Qureshy Ahmad的女王,、,第一部门,戴安娜和Sathekge,迈克和沃斯,Mariza和Sobic Saranovic, Dragana Pusuwan, Pawana曼,维拉和Vinjamuri索班和Zumla Alimuddin帕斯卡,托马斯。注意首次临床表现为肺外结核的PET/CT特征:横断面观察18 f-fdg成像研究在六个国家},体积= {55}= {2},elocation-id = {1901959} = {2020}, doi ={10.1183/13993003.01959 -2019},出版商={欧洲呼吸学会},文摘={背景的巨大的全球负担的大部分肺外结核(EPTB)病例治疗经验没有准确定义疾病的网站和多器官疾病介入的程度。188bet官网地址摘要应用2-脱氧-2-(氟-18)氟-d-葡萄糖(18F-FDG)正电子发射断层显像(PET)在结核病诊断中的应用，是一种有效的疾病定位和疾病范围的显像技术。方法我们对印度、巴基斯坦、泰国、南非、塞尔维亚和孟加拉国等6个国家的8个中心的hiv阴性成人患者进行了一项新的临床诊断EPTB的研究，以评估首次发病时的疾病程度和常见部位。两周内进行18F-FDG PET/ CT扫描。结果358例EPTB患者(女189例;169名男性)被招募超过45个月，年龄范围为18岁(女性平均30岁;男性平均38岁)。358名患者(183名女性，167名男性)中有350名(98\%)的扫描呈阳性。350人中有118人(33.7% %)只有一个肺外部位，而有232人(66.3% %)有多个肺外部位(器官)受到影响。淋巴结、骨骼、胸膜和大脑是常见的部位。 100 (28\%) out of 358 EPTB patients had 18F-FDG PET/CT-positive sites in the lung. 110 patients were 18F-FDG PET/CT-positive in more body sites than were noted clinically at first presentation and 160 patients had the same number of positive body sites.Interpretation 18F-FDG PET/CT scan has potential for further elucidating the spectrum of disease, pathogenesis of EPTB and monitoring the effects of treatment on active lesions over time, and requires longitudinal cohort studies, twinned with biopsy and molecular studies.18F-FDG PET/CT can localise EPTB disease sites not clinically detected. It may serve a useful tool for research studies defining pathogenetic mechanisms and cure, relapse and recurrence. http://bit.ly/2CKSH9a}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/55/2/1901959}, eprint = {//www.qdcxjkg.com/content/55/2/1901959.full.pdf}, journal = {European Respiratory Journal} }