RT期刊论文SR电子T1阻塞性睡眠呼吸暂停的治疗和血压:该表型预测的响应?系统回顾和荟萃分析JF欧洲呼吸杂志JO欧元呼吸杂志FD欧洲呼吸学会SP 1901945 DO 10.1183 / 13993003.01945-2019 A1彭格,马蒂诺F. A188bet官网地址1 Soranna,达维德A1 Giontella,爱丽丝A1 Perger,酶联免疫吸附A1 Mattaliano,帕乌拉A1施瓦茨,以斯帖艾琳A1隆巴迪,罗莱A1比洛,格热戈日A1赞邦,安东内拉A1 Steier,约尔格A1帕拉蒂,詹弗兰科A1 Minuz,彼得A1法瓦,克里斯蒂亚诺YR 2020 UL //www.qdcxjkg.com/content/early/2020/02/06/13993003.01945-2019.abstract AB治疗阻塞性睡眠呼吸暂停(OSA)与持续气道正压(CPAP)或下颌前移设备(MAD)与(BP)血压降低相关联。然而,整体效果是谦虚。该系统评价和比较对BP这样的治疗效果的随机对照试验的荟萃分析的目的是确定的是谁treatment.The文章搜索与特定搜索条件和选择标准,三个不同的数据库中进行反应最好亚组患者。从2289篇,我们包括随机对照试验68相比CPAP或MAD与被动或主动治疗。当所有的研究都集中在一起,CPAP和MAD与毫米汞柱[平均值(95%CI)]的平均血压降低-2.09(-2.78,-1.40),用于收缩和-1.92(-2.40相关联,-1.43)毫米汞柱的舒张压,和-1.27(-2.34,-0.20)毫米汞柱收缩压和的-1.11(-1.82,-0.41)毫米汞柱舒张压分别。The subgroups of patients who showed a greater response were those: younger than 60 years (systolic BP −2.93 mmHg), with uncontrolled BP at baseline (systolic BP −4.14 mmHg) and with severe oxygen desaturations (SpO2-nadir<77%) at baseline (24 h systolic BP −7.57 mmHg).Although this meta-analysis shows that the expected reduction of BP by CPAP/MADs is modest, it identifies specific characteristics that may predict a pronounced benefit from CPAP in terms of blood pressure control. These findings should be interpreted with caution, however, they are particularly important in identifying potential phenotypes associated with BP reduction in patients treated for OSA.FootnotesThis manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.Conflict of interest: Dr pengo has nothing to disclose.Conflict of interest: Dr Soranna has nothing to disclose.Conflict of interest: Dr Giontella has nothing to disclose.Conflict of interest: Dr Perger has nothing to disclose.Conflict of interest: Dr mattaliano has nothing to disclose.Conflict of interest: Dr Schwarz has nothing to disclose.Conflict of interest: Dr Lombardi has nothing to disclose.Conflict of interest: Dr Bilo has nothing to disclose.Conflict of interest: Dr Zambon has nothing to disclose.Conflict of interest: Dr Parati has nothing to disclose.Conflict of interest: Dr Minuz has nothing to disclose.Conflict of interest: Dr FAVA has nothing to disclose.Conflict of interest: Dr Steier has nothing to disclose.