@article {Pengo1901945,作者= {彭格,Martino的F.和Soranna,达维德和Giontella,Alice和Perger,ELISA和Mattaliano,保拉和施瓦茨,以斯帖艾琳和Lombardi,卡罗莱纳州和比洛,和的Grzegorz赞邦,安东和Steier,约尔格和帕拉蒂,詹弗兰科和Minuz,彼得和Fava的,克里斯蒂},标题= {阻塞性睡眠呼吸暂停的治疗和血压:其表型预测的响应?系统回顾和荟萃分析},elocation-ID = {1901945},年= {} 2020,DOI = {10.1183 / 13993003.01945-2019},出版商= {欧洲呼吸学会},抽象= {治疗阻塞性睡眠呼吸暂停188bet官网地址(OSA)与持续气道正压(CPAP)或下颌前移设备(MAD)与(BP)血压降低相关联。然而,总的效果是有限的。该系统评价和比较对BP这样的治疗效果的随机对照试验的荟萃分析的目的是确定的是谁treatment.The文章搜索与特定搜索条件和选择标准,三个不同的数据库中进行反应最好亚组患者。从2289篇,我们包括随机对照试验68相比CPAP或MAD与被动或主动治疗。当所有的研究都集中在一起,CPAP和MAD与平均血压降低-2.09(-2.78,-1.40)毫米汞柱[平均(95 \%CI)]为收缩压和-1.92(-2.40,相关联 -1.43)毫米汞柱的舒张压,和-1.27(-2.34,-0.20)毫米汞柱收缩压和的-1.11(-1.82,-0.41)毫米汞柱舒张压分别。谁的病人表现出较大的响应的亚组是那些:年龄小于60岁(收缩压-2.93毫米汞柱),不受控制BP在基线(收缩压-4.14毫米汞柱),并与严重的氧饱和度下降度(SpO2最低点\ <77 \%)在基线(24小时收缩压-7.57毫米汞柱)。虽然本荟萃分析表明,通过CPAP BP的预期减少/ MADS是适度的,它标识了可以预测从CPAP明显的益处在血压控制的方面的具体特征。这些调查结果应谨慎解释,但是,它们识别与在OSA.FootnotesThis稿件治疗的患者血压降低相关的潜在的表型最近已经接受了在欧洲呼吸杂志出版尤为重要。 It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.Conflict of interest: Dr pengo has nothing to disclose.Conflict of interest: Dr Soranna has nothing to disclose.Conflict of interest: Dr Giontella has nothing to disclose.Conflict of interest: Dr Perger has nothing to disclose.Conflict of interest: Dr mattaliano has nothing to disclose.Conflict of interest: Dr Schwarz has nothing to disclose.Conflict of interest: Dr Lombardi has nothing to disclose.Conflict of interest: Dr Bilo has nothing to disclose.Conflict of interest: Dr Zambon has nothing to disclose.Conflict of interest: Dr Parati has nothing to disclose.Conflict of interest: Dr Minuz has nothing to disclose.Conflict of interest: Dr FAVA has nothing to disclose.Conflict of interest: Dr Steier has nothing to disclose.}, issn = {0903-1936}, URL = {//www.qdcxjkg.com/content/early/2020/02/06/13993003.01945-2019}, eprint = {//www.qdcxjkg.com/content/early/2020/02/06/13993003.01945-2019.full.pdf}, journal = {European Respiratory Journal} }