TY - T1的肥胖的措施和慢性阻塞性肺病的风险之间的联系中国成年人摩根富林明-欧洲呼吸杂志》乔和J - 10.1183/13993003.01899 -2019欧元SP - 1901899 AU -李,Jiachen盟——朱、陆盟——魏Yuxia AU - Lv,君非盟-郭,Yu盟——扁,郑AU - Du, Huaidong AU -杨,凌AU - Chen yip盟——周Yonglin AU -高,此文非盟-陈,军师盟——陈,均非盟-曹,华盟- Yu、Canqing AU -李,李明A2 -,Y1 - 2020/01/01 UR - //www.qdcxjkg.com/content/early/2020/01/03/13993003.01899-2019.abstract N2 -体重和脂肪分布可能与慢性阻塞性肺病(COPD)风险相关。有限的前瞻性证据表明慢性阻塞性肺病与腹部肥胖有关。我们在一项前瞻性队列研究中调查了体重指数(BMI)和腹部肥胖与慢性阻塞性肺病风险的关系。中国嘉道理生物银行(CKB)从全国10个地区招募了30-79岁的参与者。人体测量指标是在2004-2008年的基线调查中客观测量的。排除流行COPD和主要慢性疾病患者后，纳入452 259例患者，随访至2016年底。我们使用Cox模型来估计肥胖与COPD住院或死亡风险之间的调整危险比。在平均10.1年的随访中，报告了10739例COPD住院事件和死亡。与正常BMI (BMI 18.5 ~ 24.0 kg·m−2)相比，体重不足(BMI 18.5 kg·m−2)的个体患慢性阻塞性肺病的风险增加，调整HR (95% CI)为1.78(1.66 ~ 1.89)。超重(BMI 24.0 ~ 28.0 kg·m−2)和肥胖(BMI≥28.0 kg·m−2)与腰围调整后风险增加无关。经BMI调整后，较高的腰围(男性≥85厘米，女性≥80厘米)与COPD风险呈正相关。 Waist-to-hip ratio and waist-to-height ratio were also positively related to COPD risk.Abdominal adiposity and underweight were risk factors for COPD in Chinese adults. Both BMI and measures of Abdominal adiposity should be considered in the prevention of COPD.FootnotesThis manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.Conflict of interest: Dr. J. Li has nothing to disclose.Conflict of interest: Dr. Zhu has nothing to disclose.Conflict of interest: Dr. Wei has nothing to disclose.Conflict of interest: Dr. Lv has nothing to disclose.Conflict of interest: Dr. Guo has nothing to disclose.Conflict of interest: Dr. Bian has nothing to disclose.Conflict of interest: Dr. Du has nothing to disclose.Conflict of interest: Dr. Yang has nothing to disclose.Conflict of interest: Dr. Chen has nothing to disclose.Conflict of interest: Dr. Zhou has nothing to disclose.Conflict of interest: Dr. Gao has nothing to disclose.Conflict of interest: Dr. J. Chen has nothing to disclose.Conflict of interest: Dr. Z. Chen has nothing to disclose.Conflict of interest: Dr. Cao has nothing to disclose.Conflict of interest: Dr. Yu has nothing to disclose.Conflict of interest: Dr. L. Li has nothing to disclose. ER -