TY-JUR T1 - 斯德哥尔摩孕妇结核病筛查和治疗JF - 欧洲呼吸杂志Jo - Eur Respir J Do - 10.1183 / 13993003 - 1900851 Au - Fröberg,Gabrielle Au - Jansson,Lena Au -Nyberg,Katherine Au - Obasi,Birgitta Au - Westling,Katarina Au - Berggren,Ingela Au - Bruchfeld,Judith Y1 - 2020/01/01 UR - //www.qdcxjkg.com/content/early/2020/01/03 / 13993003.00851-2019.Abstract N2 - 瑞典国家结核病(TB)指南建议在高处理国家(PW)中的活性和潜在的TB(LTBI)筛选或以前暴露可能改善早期检测和治疗。我们评估了级联在斯德哥尔摩县2016 - 2017年斯德哥尔摩县PW新推出的TB筛查计划的关怀。该算法包括母体保健诊所的临床数据和Qualriferon®(QFT),并在阳性测试或结核病症状后进行专科护理。29 000艾滋病毒阴性PW每年注册,其中11%来自高处理国家。2016年,其中72%的Quantiferon®(QFT)筛选,其中22%是QFT阳性,85%被称为专业护理。2017年,相应数字为64%,19%和96%。所有QFT阳性PW之间的LTBI处理率随时间增加到37%至37%。治疗完成主要是利福平产后产后的94%。在69名注册的艾滋病毒阳性PW中,78%起源于高处理国家。 Of these, 72% where screened with QFT and 15% were positive, but none was treated for LTBI. Nine HIV negative active pulmonary TB cases were detected (incidence 215/100 000). None had been screened for TB prior to pregnancy and only one had sought care due to symptoms.Systematic TB screening of PW in Stockholm was feasible with high yield of unknown LTBI and mostly asymptomatic active TB. Optimised routines improved referrals to specialist care. Treatment completion of LTBI was very high. Our findings justify TB screening of this risk group for early detection and treatment.FootnotesThis manuscript has recently been accepted for publication in the European Respiratory Journal. It is published here in its accepted form prior to copyediting and typesetting by our production team. After these production processes are complete and the authors have approved the resulting proofs, the article will move to the latest issue of the ERJ online. Please open or download the PDF to view this article.Conflict of interest: Dr. Fröberg has nothing to disclose.Conflict of interest: Dr. Jansson has nothing to disclose.Conflict of interest: Dr. Nyberg has nothing to disclose.Conflict of interest: Dr. Obasi has nothing to disclose.Conflict of interest: Dr. Westling has nothing to disclose.Conflict of interest: Dr. Berggren has nothing to disclose.Conflict of interest: Dr. Bruchfeld has nothing to disclose. ER -