PT-日记文章Au -Jhun,Byung Woo Au -Moon,Seong Mi Au -Jeon,Jeon,Kyeongman au -Kwon,O Jung Au -yoo -yoo,Heejin au -Carriere -Carriere,Keumhee C. au -C. au-Yong Au -Shin,Sung Jae Au -Daley -Daley,Charles L. Au -Koh,Won -Jung Ti-与长期死亡率有关的预后因素与1445例无效性分枝杆菌肺疾病患者:15年的随访研究帮助 -10.1183/13993003.00798-2019 DP -2020 JAN 01 TA-欧洲呼吸杂志PG -1900798 VI -55 IP -1 4099 -http://www.qdcxjkg.com/content/5555/1900798.Short 4100-1900798.short 4100- HTTP://www.qdcxjkg.com/content/55/1/1/1900798.full so -eur Respir J2020 Jan 01;55 AB - 有关无结核分枝杆菌肺疾病(NTM -PD)患者的预后因素的有限数据。我们研究了调整单个混杂因子(包括病因生物体和放射学形式)后NTM-PD患者长期死亡率相关的预后因素。总共1445例未接受治疗的NTM-PD患者,他们在1997年7月至12月之间被新诊断出来。包括2013年。病因生物如下:雄性分枝杆菌(n = 655),M。内ellulare(n = 487),M。Abscessus(n = 129)和M. massiliense(n = 174)。调整人口统计学,放射学和病因数据后,使用多变量COX模型分析了与NTM-PD患者死亡率相关的因素。NTM-PD患者的总5年,10年和15年的累积死亡率为12.4%。分别为24.0%和36.4%。在多变量分析中,以下因素与NTM-PD患者的死亡率显着相关:老年,男性,低体重指数,慢性肺曲霉菌病,肺部或肺外恶性肿瘤,慢性心脏或肝脏疾病以及红细胞降压率。病因生物也与死亡率显着相关:M。胞内的危险比(AHR)为1.40,95%CI 1.03–1.91; M. abscessus had an aHR of 2.19, 95% CI 1.36–3.51; and M. massiliense had an aHR of 0.99, 95% CI 0.61–1.64, compared to M. avium. Mortality was also significantly associated with the radiological form of NTM-PD for the cavitary nodular bronchiectatic form (aHR 1.70, 95% CI 1.12–2.59) and the fibrocavitary form (aHR 2.12, 95% CI 1.57–3.08), compared to the non-cavitary nodular bronchiectatic form.Long-term mortality in patients with NTM-PD was significantly associated with the aetiological NTM organism, cavitary disease and certain demographic characteristics.The long-term mortality of patients with nontuberculous mycobacterial pulmonary disease was significantly associated with the aetiological organism, cavitary disease and certain demographic characteristics http://bit.ly/2kyXTHT