TY -的T1 -脂肪航空:好bad fats? JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.02060-2019 VL - 54 IS - 6 SP - 1902060 AU - Brightling, Christopher E. AU - Tobin, Andrew B. AU - Milligan, Graeme Y1 - 2019/12/01 UR - //www.qdcxjkg.com/content/54/6/1902060.abstract N2 - There is a constant and consistent message in the medical and lay press that obesity is a modern epidemic affecting the developed world. It causes and exacerbates multiple diseases including cardio-metabolic, musculoskeletal, cancer and respiratory diseases [1]. There is no doubt that improving diet and lifestyle to eliminate obesity has positive health benefits [1]. Although this truism is well-known and accepted, the impact of obesity on the immunobiology of disease [1–4] is only beginning to be unravelled and this might reveal more subtle, albeit profound, effects of obesity on chronic inflammatory diseases.Adipose tissue is increased around the airway in asthma and is associated with BMI, airway inflammation and disease severity. Fat in the airway might contribute both positively and negatively to the immunobiology of asthma. http://bit.ly/2CgOGsYThis paper contains independent research funded by the National Institute for Health Research (NIHR) Leicester Respiratory Biomedical Centre. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health. ER -