％0期刊文章％A de Jong，Carmen C.M.Pedersen，Eva S.L.％a mozun，rebeca％a goutaki，myrofora％a trachsel，daniel％a barben，juerg％a Kuehni，Claudia E.患儿哮喘的％t诊断：详细历史和测试结果的贡献％d 2019％r 10.1183/13993003.01326-2019％J欧洲呼吸期杂志％p 1901326％v 54％n 6％x引言有关不同测试的有用性的数据很少有关诊断儿童哮喘的有用性。我们评估了详细历史的贡献和各种各样的贡献诊断患儿哮喘诊断试验。我们研究了6-16岁儿童的诊断，涉及涉及疑似哮喘至两种肺门诊诊所的患者。疗法调查问卷评估。临床评估包括皮肤刺的试验，通过运动，甲素和甘露醇测量呼出的一氧化氮部分（FENO），肺刺激，支气管扩张剂可逆性和支气管挑衅性试验（BPT）。在访问结束时，医生诊断出哮喘。我们通过计算曲线（AUC）下的敏感性，特异性，正负预测值和面积来评估症状和测试的诊断准确性.111参与者的结果，80（72％）被诊断出哮喘。报告频繁的喘息（每年超过三次攻击）（敏感性0.44，特异性0.90），由于喘息（0.41,0.90）和由花粉（0.46,0.83）或宠物引发的喘息（0.29,0.99）。 Of the diagnostic tests, the AUC was highest for FeNO measurement (0.80) and BPT by methacholine (0.81) or exercise (0.74), and lowest for forced expiratory volume in 1 s (FEV1) (0.62) and FEV1/forced vital capacity ratio (0.66), assessed by spirometry.Conclusion This study suggests that specific questions about triggers and severity of wheeze, measurement of FeNO and BPT by methacholine or exercise contribute more to the diagnosis of asthma in school-aged children than spirometry, bronchodilator reversibility and skin-prick tests.Diagnosing asthma in children is most accurately done by using information on triggers and severity of wheeze and by FeNO measurement, methacholine and exercise challenge tests. http://bit.ly/2kDWaRr %U //www.qdcxjkg.com/content/erj/54/6/1901326.full.pdf