％0期刊文章％Modarezi，Mohammad Reza％Navaie，Safura％Shirzadi，Rouhollah％AKEYVANFAR，MAJD％T伊朗的Majd％T囊性纤维化2019％D 2019％R 10.1183/139993003％p PA4525％v 54％n Suppl 63％x背景：囊性纤维化（CF）作为致命的遗传条件，与高发病率和死亡率高有关。在伊朗，对这种疾病的研究有限。这项研究旨在比较CF患者的人口统计，临床和旁路数据。方法：这项横断面研究于2014 - 2015年对174名CF患者进行了转诊为Tehran儿童医疗中心医院，这是CF的主要转诊中心。在174名患者中测量了一秒钟（FEV1）的强制呼气量。记录了患者的人口统计学，临床和实验室数据。结果：总体而言，有59％的研究患者为男孩（n = 102），41％是女孩（n = 72）。患者的平均（标准偏差）年龄为7.1（5.7）年，范围为10天至28年。在67％的病例中，该疾病在第一个生日之前被诊断出。在测量FEV1的患者中，分别记录了62％，33％和5％的病例。据报道，铜绿假单胞菌和金黄色葡萄球菌的呼吸道分泌物培养物为阳性，分别为23％和16％的病例。 In total, 61% of patients (n=83) used oral azithromycin for prophylaxis. Gastro-esophageal reflux disease (35%), osteopenia (22%) and nasal polyps (13%) were the most common complications in the study population.Conclusion: Regarding the complex nature of cystic fibrosis and the necessity of constant monitoring of patients during the life-span, the demographic, clinical and laboratory analysis of patients and registering and standardization of patients’ data, can be a major step in the better understanding of the disease and thereby increasing the quality of life and life expectancy in the affected population.FootnotesCite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA4525.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). %U