PT - 杂志 - 雷梅斯，格伦·奥尔 - 德·赫达特，Anelies Au - Ides，Kris Au - Van Holsbeke，Cedric Au - Belmans，Dennis Au - Becker，Brian Au - Van Hoorenbeeck，Kim Ti - 移动HFCWO设备的有效性对于Airway清关：对HyperInflation Aid的影响 - 10.1183 / 13993003 .Congress-2019.Pa4528 DP - 2019年9月28日TA - 欧洲呼吸期刊PG - PA4528 VI - 54 IP - Spect 63 4099 - //www.qdcxjkg.com/Content / 54 / sprev_63 / pa4528.short 4100 - //www.qdcxjkg.com/content/54/suppl_63/pa4528.full so - eur Respir J2019 9月28日;54 AB - 简介：高频胸壁振荡（HFCWO）是囊性纤维化患者常用的气道清理技术（ACT）。然而，HFCWO设备的可用性取决于交流电源。本研究旨在评估新移动HFCWO设备（MHFCWO）（MOHFCWO）（MONARCH®系统）的有效性。方法：这是一个随机的开放标签的交叉研究。受试者随机分为MHFCWO或标准非移动HFCWO设备（SHFCWO）（VEST®系统）。治疗是30分钟，每种装置都有多个频率和强度设置。受试者在30分钟的治疗期间收集痰和治疗后一小时。在治疗前和痰收集后完成肺活量和HRCT扫描。使用BRODY评分和功能性呼吸成像（FRI）来评估肺部状态和气道几何形状。结果：8稳定的CF患者完成了该研究。 Mean wet sputum weight and spirometry parameters were similar between mHFCWO and sHFCWO (figure1). Brody scores showed statistically significant improvement after therapy with mHFCWO (figure1). Additionally, FRI showed statistically significant differences in airway geometry and patency (siVaw/siRaw) suggesting mucus shifting with a reduction in regional lobar volume (iVlobe)-(figure1).Conclusion: mHFCWO (Monarch® System) provides effective ACT in CF patients with a shift in mucus and a reduction in hyperinflation.FootnotesCite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA4528.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).