TY - JOUR T1 - COPD单药吸入皮质类固醇治疗与COPD伴哮喘初级护理治疗的预测因子PA5006六世- 54 - 5 63 SP - PA5006盟Savran奥斯曼盟——Godtfredsen尼娜AU - Sørensen,托本盟-詹森,基督教盟——恋爱补给品Ulrik,夏洛特Y1 - 2019/09/28 UR - //www.qdcxjkg.com/content/54/suppl_63/PA5006.abstract N2 -背景和目的:吸入糖皮质激素(ICS)可能在一般实践中被过度处方COPD。我们的目的是确定在普通实践中对COPD患者有或没有哮喘的患者开ICS处方的预测因素。方法:参与的全科医生(n=144)招募COPD患者(ICPC第二版，代码R95)和目前处方的ICS (ACT代码R03AK和R03BA)。从病历中检索人口统计学、吸烟习惯、肺活量测定、呼吸困难评分和病情加重史等数据。Pearson卡方检验用于分类变量的比较，logistic回归分析用于确定哮喘诊断的预测因素。结果:共招募2.289例患者。与COPD单独患者(n=1.749)相比，COPD和哮喘患者(n=540)更年轻，BMI更高，FEV1/FVC比率更高(分别为0.56和0.62)，血液嗜酸性粒细胞计数更高，终生烟草暴露更少(分别为36和26包年)。根据GOLD肺功能分级，COPD和哮喘患者的病情较单独COPD患者轻(p;0.001)。与COPD单独相比，logistic回归分析显示COPD合并哮喘与年龄相关(p; OR 1.06; CI 1.03 to 1.09; p<0.001), pack-years of smoking (OR 0.98; CI 0.97 to 0.99; p=0.001), FEV1%pred (OR 1.02; CI 1.01 to 1.04; p=0.003), and doctor-diagnosed depression (p = 0.023; OR 2.4; CI 1.1 to 5.1; p=0.023).Conclusion: In COPD patients currently prescribed ICS, a diagnosis of concomitant asthma was predicted by younger age, less tobacco exposure, and more preserved lung function compared to COPD alone.FootnotesCite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA5006.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). ER -