TY - JOUR T1 -儿童囊性纤维化患者药物治疗依从性的评估;JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2019。PA4520 VL - 54 IS - supp63 SP - PA4520 AU - Amini, Shahideh AU - Jafarrangraz, Saedeh Sadat AU - Modaresi, Mohammadreza AU - Gholami, Kheirollah Y1 - 2019/09/28 UR - //www.qdcxjkg.com/content/54/suppl_63/PA4520.abstract N2 -背景:囊性纤维化是一种复杂的，多系统损害与多药，影响儿童和他们的父母。坚持治疗对优化CF疾病管理至关重要。目的和目的:本研究的目的是评估这一人群的药物依从性，并确定影响依从性的因素。方法:对伊朗儿童医疗中心CF门诊的CF门诊患者进行观察性前瞻性研究。连续招募CF患儿及其父母。通过访谈和复查病历收集基线数据、病史、临床结局数据。采用Morisky药物治疗依从性量表(MMAS)测量依从性。结果:300例CF患者(年龄1-25岁，平均7.6岁，58.7%为男性)和父母对被招募。 The mean score of MMAS in pulmonary, antibiotics, gastrointestinal and supplement medications was 5.1, 4.6, 4.1 and 3.3 respectively. According to the categorization of Morisky Scale, 58% of patients who received inhaler medications and 65% of patients who received antibiotics had a low adherence (lower than 6 scores). High adherence was associated with child age, parental higher educational degree and their beliefs, duration of illness and frequency of healthcare visit ((P=0.001).Conclusion: The results indicated that the non-adherence was very common in patients with CF. Our results suggest the need for educational interventions and planned patient monitoring program in patients with CF to optimize management and health outcomes.FootnotesCite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA4520.This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only). ER -