TY - T1的捐赠者的影响,接受者和匹配高紧急肺移植后生存在法国JF -欧洲呼吸杂志》乔和J - 10.1183/13993003.00096 -2019欧元六世- 54 - 5 SP - 1900096 AU Roussel Arnaud盟——圣人,爱德华。非盟- Massard里展现变换,吉尔伯特AU -托马斯,Pascal-Alexandre盟——CastierYves Fadel,非盟-埃利非盟- Le Pimpec-Barthes,弗朗索瓦丝盟——Maury jean - michel盟——Jougon雅克盟——鳄鱼,菲利普盟——Claustre Johanna盟——Dahan Marcel盟——Pirvu Augustin盟——天梭,阿德里安·盟——Thumerel马修盟——Drevet加布里埃尔盟——Pricopi Ciprian AU - Le Pavec杰罗姆AU - Mal Herve AU - D 'Journo,Xavier-Benoit AU - Kessler, Romain AU - Roux, Antoine AU - Dorent, Richard AU - thabet, Gabriel AU - Mordant, Pierre A2 -, Y1 - 2019/11/01 UR - //www.qdcxjkg.com/content/54/5/1900096.abstract N2 -介绍自2007年7月以来,法国的高紧急肺移植分配程序将可用的肺移植优先分配给有迫在眉睫的死亡风险的等待患者。供者、受者和匹配对HELT后结果的相对影响尚不清楚。我们的目标是在一个详尽的行政数据库中解释捐助者、受援者和匹配对HELT之后的结果的相对影响。方法:所有在法国进行的肺移植都前瞻性地登记在一个管理数据库中。我们回顾性回顾了2007年7月至2015年12月间进行的手术,并通过拟合边缘Cox模型,分析了供体、受体和匹配对HELT术后总生存期的影响。结果在研究期间,2335名患者在11个法国中心接受了肺移植。排除慢性阻塞性肺疾病/肺气肿患者后,1544例患者纳入:503例HELT和1041例标准肺移植。HELT与死亡的危险比为1.41 (95% CI 1.22-1.64;p<0.0001),在多变量模型中纳入受体特征后下降至1.32 (95% CI 1.10-1.60)。 A donor score computed to predict long-term survival was significantly different between the HELT and standard lung transplantation groups (p=0.014). However, the addition of donor characteristics to recipient characteristics in the multivariate model did not change the hazard ratio associated with HELT.Conclusions This exhaustive French national study suggests that HELT is associated with an adverse outcome compared with regular allocation. This adverse outcome is mainly related to the severity status of the recipients rather than donor or matching characteristics.The results of this first exhaustive multicentre French national study suggest that adverse outcomes associated with high emergency lung transplantation are mainly related to the severity status of recipients rather than donor or matching characteristics http://bit.ly/2LSyWTE ER -