RT期刊论文SR电子T1气道形态与支气管扩张COPD：对所有气道世代的图JF欧洲呼吸杂志JO欧洲呼吸ĴFD欧洲呼吸协会SP 1802166 DO 10.1183 / 13993003.02166-2018 VO 54 5个A1 Everaerts，斯蒂芬妮A1麦克唐纳188bet官网地址约翰E. A1 Verleden，斯泰恩E. A1约西波维奇，伊万A1布恩，马修A1 Dubbeldam，阿德里安娜A1 Mathyssen，Carolien A1 SERRE，杰夫A1杜邦，利芬J. A1加扬-Ramirez的，吉莱纳A1 Verschakelen，约翰尼拉A1霍格，詹姆斯çA1。Verleden，吉尔特M. A1 Vanaudenaerde，巴特M. A1 Janssens的，维姆YR 2019 UL //www.qdcxjkg.com/content/54/5/1802166.abstract AB的病理生理过程中慢性阻塞性肺病底层支气管扩张（COPD）不被理解。在慢性阻塞性肺病，小型和大型航空公司正在逐渐丧失。它目前还不知道到什么程度的COPD患者和支气管扩张不同的气道几代人involved.COPD植肺支气管扩张进行了比较，COPD植肺支气管扩张没有和未使用的供体肺作为对照。为了调查所有气道代，采用不同分辨率的多模成像方法被进行。每组五个肺冷冻（N = 15）和大气道评估后行计算机断层扫描（CT）成像，以用于成像终末细支气管的测量每个肺4个组织核心。每组两个额外的肺（N = 6）为大叶性肺炎显微CT图像，其允许相对于COPD肺而不支气管扩张（对气道分割和支气管扩张的气道完全tree.COPD肺的三维量化有显著更呼吸道风干<0.001），类似于控制肺部气道的大数字。这种差异存在于两个上部和下部凸角。 Lack of tapering was present (p=0.010) and larger diameters were demonstrated in lower lobes with bronchiectasis (p=0.010). MicroCT analysis of tissue cores showed similar reductions of tissue percentage, surface density and number of terminal bronchioles in both COPD groups compared to control lungs.Although terminal bronchioles were equally reduced in COPD lungs with and without bronchiectasis, significantly more large and small airways were found in COPD lungs with bronchiectasis.Although terminal bronchioles are equally reduced in COPD lungs with and without bronchiectasis, significantly more large and small airways are found in COPD lungs with bronchiectasis http://bit.ly/2YJ5kKs