RT期刊文章SR电子T1结核病在意大利米兰寻求庇护者：流行病学分析和干预措施的评估JF欧洲呼吸杂志Jo Eur Respir J FD欧洲呼吸学会SP 1900896 DO 10.1183/139993003.00896-2019-2019 vo 54 vo 54 IS 4 A11 a1 a1 a1 a1 a1 a1 a1 a1 a1 a1188bet官网地址Codecasa, Luigi Ruffo A1 Faccini, Marino A1 Pontello, Mirella Maria A1 Ferrarese, Maurizio A1 Castellotti, Paola Francesca A1 Senatore, Sabrina A1 Lamberti, Anna A1 Mazzola, Ester A1 Perno, Carlo Federico A1 Campisi, Daniela A1 Saporiti, Matteo A1 Raviglione,Mario Carlo YR 2019 UL //www.qdcxjkg.com/content/54/4/1900896.Abstract在欧盟国家/地区，结核病（TB）主要影响边缘化的人，包括庇护所在内。从高侵略国家到意大利的迁徙流量已经增加到2017年，对国家卫生体系构成了挑战。这项研究试图评估米兰在2016 - 2017年期间米兰寻求庇护者中的结核病和潜在结核病感染（LTBI）患病率，并评估了针对TB和LTBI的两级主动监视和筛查系统。寻求庇护者在接收地点进行了结核蛋白皮肤测试（TST）和问卷调查的初始筛查。在区域结核病参考中心，具有阳性结果的人进行了胸部X线摄影。老年人<35岁的胸部射线照相负阴性的人通过干扰素-γ释放分析进行了进一步的测试。如果测定结果为阳性，则提供LTBI治疗。将TB和LTBI患病率与文献数据进行了比较。总共有5324名寻求庇护者，主要是年轻（10-39岁； 98％），男性（84％）和撒哈拉以南非洲（69％），招募了该研究。。 69 active TB cases were diagnosed and 863 LTBI-positive individuals were detected. TB prevalence was high (1236 per 100 000 population) and LTBI prevalence was 28%. Despite losses (41%) during the transition from initial screening sites and the diagnostic centre, a good TB cure rate (84%) and optimal LTBI treatment completion (94%) were achieved.Our study shows that TB incidence is high among asylum seekers in Milan and that well-coordinated screening measures are critical for early diagnosis and treatment. It also proves that rolling out successful at-scale interventions for both prophylaxis and disease management is feasible.Asylum seekers are vulnerable to TB owing to migration-related events and marginalisation in destination countries. Coordinated screening and surveillance programmes using well-informed datasets can reduce TB transmission, improve care and address LTBI. http://bit.ly/2SPp0uZ