TY - T1的肺结核在庇护寻求者在米兰,意大利:流行病学分析和评价干预措施的JF -欧洲呼吸杂志》乔和J - 10.1183/13993003.00896 -2019欧元六世- 54 - 4 SP - 1900896 AU -别墅,西蒙盟——Codecasa Luigi Ruffo AU - Faccini,马里诺盟——Pontello董事长米莱拉•玛丽亚AU - Ferrarese Maurizio盟——Castellotti Paola弗朗西斯卡AU - Senatore,塞布丽娜盟——该行安娜盟——Mazzola酯非盟- Perno,卡洛费德里科•盟——Campisi Daniela盟——Saporiti Matteo AU - Raviglione,马里奥·卡洛Y1 - 2019/10/01 UR - //www.qdcxjkg.com/content/54/4/1900896.abstract N2 -在欧盟国家,结核病(TB)主要影响被边缘化的人,包括寻求庇护者。迁徙从高发病率国家流向意大利已经增加了2017,全国卫生系统构成挑战。本研究试图评估结核病发病率和潜伏性结核感染(LTBI)寻求庇护者在米兰在2016 - 2017双年度评估干预措施到位。两级主动监测和筛查系统是结核病和LTBI开发的。寻求庇护者进行了初步筛选与结核菌素皮肤试验(TST)和问卷在接收站点。在地区结核病参考中心,那些积极的结果进行胸部x线摄影。人年龄& lt; 35年负面评价胸片结果进行进一步测试interferon-γ释放试验。如果化验结果是积极的,LTBI治疗了。结核病和LTBI患病率与文献数据比较。共有5324名寻求庇护者,大多是年轻(10-39年;98%),男性(84%)和来自撒哈拉以南非洲(69%),加入了这项研究。 69 active TB cases were diagnosed and 863 LTBI-positive individuals were detected. TB prevalence was high (1236 per 100 000 population) and LTBI prevalence was 28%. Despite losses (41%) during the transition from initial screening sites and the diagnostic centre, a good TB cure rate (84%) and optimal LTBI treatment completion (94%) were achieved.Our study shows that TB incidence is high among asylum seekers in Milan and that well-coordinated screening measures are critical for early diagnosis and treatment. It also proves that rolling out successful at-scale interventions for both prophylaxis and disease management is feasible.Asylum seekers are vulnerable to TB owing to migration-related events and marginalisation in destination countries. Coordinated screening and surveillance programmes using well-informed datasets can reduce TB transmission, improve care and address LTBI. http://bit.ly/2SPp0uZ ER -