PT -期刊文章盟别墅,西蒙盟——Codecasa Luigi Ruffo AU - Faccini,马里诺盟——Pontello董事长米莱拉•玛丽亚AU - Ferrarese Maurizio盟——Castellotti Paola弗朗西斯卡AU - Senatore,塞布丽娜盟——该行安娜盟——Mazzola酯非盟- Perno,卡洛费德里科•盟——Campisi Daniela盟——Saporiti Matteo盟——Raviglione马里奥·卡洛:意大利米兰寻求庇护者中的肺结核患者:流行病学分析和评价干预措施的援助- 10.1183/13993003.00896 -2019 DP - 2019年10月01 TA -欧洲呼吸杂志》第六PG - 1900896 - 54 IP - 4 4099 - //www.qdcxjkg.com/content/54/4/1900896.short 4100 - //www.qdcxjkg.com/content/54/4/1900896.full所以欧元和J2019 10月01;54 AB -在欧盟国家，结核病主要影响边缘化人群，包括寻求庇护者。截至2017年，从高发国家流向意大利的移民人数有所增加，对国家卫生系统构成了挑战。本研究旨在评估2016-2017两年期米兰寻求庇护者中的结核病和潜伏结核病感染(LTBI)患病率，并评估采取的干预措施。为结核病和LTBI开发了一个两级主动监测和筛查系统。寻求庇护者在接收地点接受了结核菌素皮肤试验(TST)的初步筛查和问卷调查。在区域结核病参考中心，对结果呈阳性的患者进行了胸片检查。对35岁胸片阴性的患者进行干扰素-γ释放试验。如果检测结果为阳性，则给予LTBI治疗。 TB and LTBI prevalence were compared with literature data.A total of 5324 asylum seekers, mostly young (10–39 years; 98%), male (84%) and from sub-Saharan Africa (69%), were enrolled in the study. 69 active TB cases were diagnosed and 863 LTBI-positive individuals were detected. TB prevalence was high (1236 per 100 000 population) and LTBI prevalence was 28%. Despite losses (41%) during the transition from initial screening sites and the diagnostic centre, a good TB cure rate (84%) and optimal LTBI treatment completion (94%) were achieved.Our study shows that TB incidence is high among asylum seekers in Milan and that well-coordinated screening measures are critical for early diagnosis and treatment. It also proves that rolling out successful at-scale interventions for both prophylaxis and disease management is feasible.Asylum seekers are vulnerable to TB owing to migration-related events and marginalisation in destination countries. Coordinated screening and surveillance programmes using well-informed datasets can reduce TB transmission, improve care and address LTBI. http://bit.ly/2SPp0uZ